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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 15, Number 1, 2014

Articles

Open Access Editorial (Thematic Issue:Targeting Loss of Tumor Suppressors for Cancer Therapeutics)
pp. 1-1(1)
Authors: R. Prosperi, Jenifer; Heppner Goss, Kathleen

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Open Access Targeting Tumor Suppressor Networks for Cancer Therapeutics
pp. 2-16(15)
Authors: Emily Guo, Xuning; Ngo, Bryan; Sandaldjian Modrek, Aram; Lee, Wen-Hwa

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Open Access Targeting the BRCA1/2 Tumor Suppressors
pp. 17-31(15)
Authors: M. Rosen, Eliot; J. Pishvaian, Michael

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Open Access Targeting the LKB1 Tumor Suppressor
pp. 32-52(21)
Authors: Zhao, Rui-Xun; Xu, Zhi-Xiang

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Open Access Translating Mismatch Repair Mechanism into Cancer Care
pp. 53-64(12)
Author: D. Heinen, Christopher

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Open Access Therapeutic Targeting of Cancers with Loss of PTEN Function
pp. 65-79(15)
Authors: M. Dillon, Lloye; W. Miller, Todd

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Open Access Targeting Tumor Suppressor p53 for Cancer Therapy: Strategies, Challenges and Opportunities
pp. 80-89(10)
Authors: Hong, Bo; Pieter J. van den Heuvel, A.; V. Prabhu, Varun; Zhang, Shengliang; S. El-Deiry, Wafik

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Open Access Exploiting APC Function as a Novel Cancer Therapy
pp. 90-102(13)
Authors: C. Lesko, Alyssa; H. Goss, Kathleen; R. Prosperi, Jenifer

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Open Access The RNA-Dependent-RNA Polymerase, an Emerging Antiviral Drug Target for the Hendra Virus
pp. 103-113(11)
Authors: Velkov, Tony; Carbone, Vincenzo; Akter, Jesmin; Sivanesan, Sivashangarie; Li, Jian; Beddoe, Travis; A. Marsh, Glenn

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Open Access MDM2-p53 Interaction in Paediatric Solid Tumours: Preclinical Rationale, Biomarkers and Resistance
pp. 114-123(10)
Authors: Barone, Giuseppe; A. Tweddle, Deborah; M. Shohet, Jason; Chesler, Louis; Moreno, Lucas; DJ Pearson, Andrew; Van Maerken, Tom

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Open Access Genomic Identification of Potential Targets Unique to Candida albicans for the Discovery of Antifungal Agents
pp. 136-149(14)
Authors: Tripathi, Himanshu; Luqman, Suaib; Meena, Abha; Khan, Feroz

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