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Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal will be devoted to a single timely topic, with series of in-depth reviews, written by leaders in the field, covering a range of current topics on drug targets. These issues will be organized and led by a guest editor who is a recognized expert in the overall topic. As the discovery, identification, characterisation and validation of novel human drug targets for drug discovery continues to grow; this journal will be essential reading for all pharmaceutical scientists involved in drug discovery and development.

Publisher: Bentham Science Publishers

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Volume 14, Number 12, 2013

Articles

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Anti-IL-12/23 in Crohn's Disease: Bench and Bedside
pp. 1379-1384(6)
Authors: Niederreiter, Lukas; Erik Adolph, Timon; Kaser, Arthur

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Janus Kinase Inhibition with Tofacitinib: Changing the Face of Inflammatory Bowel Disease Treatment
pp. 1385-1391(7)
Authors: Vuitton, Lucine; Koch, Stephane; Peyrin-Biroulet, Laurent

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Clinical Strategies for the Blockade of IL-18 in Inflammatory Bowel Diseases
pp. 1392-1399(8)
Authors: Kanai, Takanori; Kamada, Nobuhiko; Hisamatsu, Tadakazu

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TGF-Beta Signaling Manipulation as Potential Therapy for IBD
pp. 1400-1404(5)
Authors: Marafini, Irene; Zorzi, Francesca; Codazza, Sefora; Pallone, Francesco; Monteleone, Giovanni

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Review: New Anti-Cytokines for IBD: What is in the Pipeline?
pp. 1405-1420(16)
Authors: Scharl, Michael; R. Vavricka, Stephan; Rogler, Gerhard

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Anti-TNF Antibodies in Inflammatory Bowel Disease: Do We Finally Know How it Works?
pp. 1421-1432(12)
Authors: Oikonomopoulos, Angelos; K. van Deen, Welmoed; W. Hommes, Daniel

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Anti-IL-13 in Inflammatory Bowel Disease: From the Bench to the Bedside
pp. 1444-1452(9)
Authors: Jovani, Manol; Fiorino, Gionata; Danese, Silvio

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Cell Therapies for IBD: What Works?
pp. 1453-1459(7)
Authors: Ricart, Elena; Jauregui-Amezaga, Aranzazu; Ordas, Ingrid; Pino, Susana; M. Ramirez, Anna

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Sealing the Broken Barrier in IBD: Intestinal Permeability, Epithelial Cells and Junctions
pp. 1460-1470(11)
Authors: Fries, Walter; Belvedere, Alessandra; Vetrano, Stefania

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Is There Still a Room for Azathioprine Monotherapy in Inflammatory Bowel Disease?
pp. 1471-1479(9)
Authors: Bourrier, Anne; Seksik, Philippe; Cosnes, Jacques

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Methotrexate: Should We Start Using it in Clinical Practice?
pp. 1480-1489(10)
Authors: Miheller, Pal; S. Kiss, Lajos; Mandel, Michael; L. Lakatos, Peter

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Leukocyte Traffic Blockade as a Therapeutic Strategy in Inflammatory Bowel Disease
pp. 1490-1500(11)
Authors: Bamias, Giorgos; J. Clark, David; Rivera-Nieves, Jesus

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PPAR-Gamma in Ulcerative Colitis: A Novel Target for Intervention
pp. 1501-1507(7)
Authors: Bertin, Benjamin; Dubuquoy, Laurent; Colombel, Jean-Frederic; Desreumaux, Pierre

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Anti-IL-6 Treatment for Inflammatory Bowel Diseases: Next Cytokine, Next Target
pp. 1508-1521(14)
Authors: Allocca, Mariangela; Jovani, Manol; Fiorino, Gionata; Schreiber, Stefan; Danese, Silvio

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