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Aripiprazole-Induced Pathological Gambling: A Report of 3 Cases

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We report three cases of pathological gambling induced by Aripiprazole, in patients with schizophrenia or schizoaffective disorder. All three patients had no history of pathological gambling, and they started gambling after initiation of treatment with Aripiprazole. The fact that pathological behavior disappeared quickly as medication ends suggests that an elaborate behavioral manifestation could be related to dopaminergic tone in patients with schizophrenia. We recommend consideration with increased attention for the appearance of pathological gambling symptoms among patients on Aripiprazole.

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Keywords: Age; Amilsupride; Aripiprazole; DSM -IV; Gender (M/F); Haldol; Hypersexuality; ICD; MCL; MINI; PG; Pathological Gambling; Pathological gambling; Risperidone; SOGS; behavioral addiction; bipolar disorder; compulsive eating; dopamine D3 receptor; dopamine agonist; dopaminergic; hypersexuality; schizoaffective disorder; schizophrenia; stimulation

Document Type: Research Article

Publication date: February 1, 2011

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  • Current Drug Safety publishes frontier reviews on all the latest advances on drug safety. The journal's aim is to publish the highest quality review articles in the field. Topics covered include: adverse effects of individual drugs and drug classes, management of adverse effects, pharmacovigilance and pharmacoepidemiology of new and existing drugs, post-marketing surveillance. The journal is essential reading for all researchers and clinicians involved in drug safety.
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