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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 18, Number 6, 2017

Articles

Free Content Graphical Abstracts
pp. i-iv(4)

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Free Content Meet Our Editorial Board Member
pp. 497-497(1)
Author: A. Rodrigues, David

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Free Content Editorial: Theoretical Studies of the Metabolism in Drug Discovery
pp. 498-499(2)
Authors: T. Scotti, Marcus; Scotti, Luciana

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CORAL Software: Analysis of Impacts of Pharmaceutical Agents Upon Metabolism via the Optimal Descriptors
pp. 500-510(11)
Authors: A. Toropova, Mariya; Raska Jr, Ivan; P. Toporova, Alla; Raskova, Maria

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Quantum Mechanical (QM) Calculations Applied to ADMET Drug Prediction: A Review
pp. 511-526(16)
Authors: F. Silva-JĂșnior, E.; M. Aquino, T.; X. Araujo-Junior, J.

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Helix-Coil Transition Signatures B-Raf V600E Mutation and Virtual Screening for Inhibitors Directed Against Mutant B-Raf
pp. 527-534(8)
Authors: Bandaru, Srinivas; Gangadharan Sumithnath, Tharaparambil; Sharda, Saphy; Lakhotia, Sanskruti; Sharma, Anudeep; Jain, Amrita; Hussain, Tajamul; Nayarisseri, Anuraj; Kumar Singh, Sanjeev

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In-silico ADME Studies for New Drug Discovery: From Chemical Compounds to Chinese Herbal Medicines
pp. 535-539(5)
Authors: Yan, Guojun; Wang, Xiaobing; Chen, Zhou; Wu, Xianhui; Pan, Jinhuo; Huang, Yushen; Wan, Gang; Yang, Zhaogang

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Towards Predicting the Cytochrome P450 Modulation: From QSAR to Proteochemometric Modeling
pp. 540-555(16)
Authors: Shoombuatong, Watshara; Prathipati, Philip; Prachayasittikul, Veda; Schaduangrat, Nalini; Ahmad Malik, Aijaz; Pratiwi, Reny; Wanwimolruk, Sompon; E. S. Wikberg, Jarl; Paul Gleeson, Matthew; Spjuth, Ola; Nantasenamat, Chanin

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Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools
pp. 556-565(10)
Authors: T. Issa, Naiem; Wathieu, Henri; Ojo, Abiola; W. Byers, Stephen; Dakshanamurthy, Sivanesan

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In silico and In vivo Toxicological Evaluation of Cissampelos Sympodialis Secondary Metabolites in Rattus Norvegicus
pp. 566-576(11)
Authors: F. Alves, Mateus; T. Scotti, Marcus; B. Felix, Mayara; M. Ishiki, Hamilton; Rodrigues Melo, Cinthia; F. Ribeiro, Frederico; F. Tavares, Josean; M.B. Filho, Jose; M. de Oliveira, Kardilandia; F. R. de Paula, Andrea; J. B. Mendonca Jr., Francisco; Scotti, Luciana; R. da Paz, Alexandre; G. dos Santos, Socrates; de F. F. M. Diniz, Margareth

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In-silico Design and ADMET Studies of Natural Compounds as Inhibitors of Xanthine Oxidase (XO) Enzyme
pp. 577-593(17)
Authors: Malik, Neelam; Dhiman, Priyanka; Khatkar, Anurag

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