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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 14, Number 1, 2013

Articles

Preface
pp. 1-1(1)
Author: Prakash, Chandra

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Models to Predict Intestinal Absorption of Therapeutic Peptides and Proteins
pp. 4-20(17)
Authors: Antunes, Filipa; Andrade, Fernanda; Ferreira, Domingos; Morck Nielsen, Hanne; Sarmento, Bruno

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Why We Need Proper PBPK Models to Examine Intestine and Liver Oral Drug Absorption
pp. 57-79(23)
Authors: C.Y. Chow, Edwin; Sandy Pang, K.

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Evaluation of the Physicochemical and Biopharmaceutical Properties of Fluoro-Indomethacin
pp. 80-89(10)
Authors: M. Mori, Michela; J. Airaksinen, Anu; T. Hirvonen, Jouni; A. Santos, Helder; M. Caramella, Carla

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In Vitro Methods to Study the Interplay of Drug Metabolism and Efflux in the Intestine
pp. 102-111(10)
Authors: Siissalo, Sanna; T. Heikkinen, Aki

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Precision-cut Intestinal Slices as In Vitro Tool for Studies on Drug Metabolism
pp. 112-119(8)
Authors: M.M. Groothuis, Geny; A.M. de Graaf, Inge

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Function and Regulation of the Cyp2a5/CYP2A6 Genes in Response to Toxic Insults in the Liver
pp. 137-150(14)
Authors: Abu-Bakar, A'edah; Hakkola, Jukka; Juvonen, Risto; Rahnasto-Rilla, Minna; Raunio, Hannu; A. Lang, Matti

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Metabolism of the Antituberculosis Drug Ethionamide
pp. 151-158(8)
Authors: Vale, Nuno; Gomes, Paula; A. Santos, Helder

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