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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 12, Number 10, 2011

Articles

Pharmacokinetic and Metabolism Determinants of Fluoropyrimidines and Oxaliplatin Activity in Treatment of Colorectal Patients
pp. 918-931(14)
Authors: Gnoni, Antonio; Russo, Antonio; Silvestris, Nicola; Maiello, Evaristo; Vacca, Angelo; Marech, Ilaria; Numico, Gianmauro; Paradiso, Angelo; Lorusso, Vito; Azzariti, Amalia

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Pharmacokinetic and Pharmacogenetic Predictive Markers of Irinotecan Activity and Toxicity
pp. 932-943(12)
Authors: Di Paolo, Antonello; Bocci, Guido; Polillo, Marialuisa; Del Re, Marzia; Di Desidero, Teresa; Lastella, Marianna; Danesi, Romano

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Predicting Efficacy and Toxicity in the Era of Targeted Therapy: Focus on Anti-EGFR and Anti-VEGF Molecules
pp. 944-955(12)
Authors: Caraglia, Michele; Santini, Daniele; Bronte, Giuseppe; Rizzo, Sergio; Sortino, Giovanni; Battista Rini, Giovam; Di Fede, Gaetana; Russo, Antonio

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DNA Copy Number Profiles Correlate with Outcome in Colorectal Cancer Patients Treated with Fluoropyrimidine/Antifolate-based Regimens
pp. 956-965(10)
Authors: G. Leon, Leticia; Giovannetti, Elisa; Smid, Kees; P.P. van Houte, Bart; R. Hanauske, Axel; Giaccone, Giuseppe; J. Peters, Godefridus

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Alternative Spliced Variants as Biomarkers of Colorectal Cancer
pp. 966-974(9)
Authors: Yi, Qian; Tang, Liling

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The Impact of Folate Status on the Efficacy of Colorectal Cancer Treatment
pp. 975-984(10)
Authors: Porcelli, Letizia; G. Assaraf, Yehuda; Azzariti, Amalia; Paradiso, Angelo; Jansen, Gerrit; J. Peters, Godefridus

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Clinical Pharmacokinetic and Metabolism of PET Radiotracers for Imaging P-glycoprotein in Chemoresistant Tumor of Colorectal Cancer
pp. 985-988(4)
Authors: Cantore, Mariangela; Capparelli, Elena; Berardi, Francesco; Perrone, Roberto; Antonio Colabufo, Nicola

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Toxicities by Herbal Medicines with Emphasis to Traditional Chinese Medicine
pp. 989-996(8)
Authors: Efferth, Thomas; Kaina, Bernd

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Humanized Transgenic Mouse Models for Drug Metabolism and Pharmacokinetic Research
pp. 997-1006(10)
Authors: Shen, Hong-Wu; Jiang, Xi-Ling; J. Gonzalez, Frank; Yu, Ai-Ming

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