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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 8, Number 4, 2007

Articles

Expression and Function of Cytochrome P450 in Brain Drug Metabolism
pp. 297-306(10)
Authors: Meyer, R. P.; Gehlhaus, M.; Knoth, R.; Volk, B.

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CYP-Mediated Clozapine Interactions: How Predictable Are They?
pp. 307-313(7)
Authors: Chetty, Manoranjenni; Murray, Michael

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The Non-ABC Drug Transporter RLIP76 (RALBP-1) Plays a Major Role in the Mechanisms of Drug Resistance
pp. 315-323(9)
Authors: Awasthi, Yogesh C.; Sharma, Rajendra; Yadav, Sushma; Dwivedi, Seema; Sharma, Abha; Awasthi, Sanjay

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Role of P-Glycoprotein in the Intestinal Absorption of Tanshinone IIA, a Major Active Ingredient in the Root of Salvia miltiorrhiza Bunge
pp. 325-340(16)
Authors: Yu, Xi-Yong; Lin, Shu-Guang; Zhou, Zhi-Wei; Chen, Xiao; Liang, Jun; Liu, Pei-Qing; Duan, Wei; Chowbay, Balram; Wen, Jing-Yuan; Li, Chun-Guang; Zhou, Shu-Feng

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Evaluation of Drug-Transporter Interactions Using In Vitro and In Vivo Models
pp. 341-363(23)
Authors: Xia, Cindy Q.; Milton, Mark N.; Gan, Liang-Shang

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Transport of Cryptotanshinone, a Major Active Triterpenoid in Salvia Miltiorrhiza Bunge Widely Used in the Treatment of Stroke and Alzheimer's Disease, Across the Blood-Brain Barrier
pp. 365-377(13)
Authors: Yu, Xi-Yong; Lin, Shu-Guang; Chen, Xiao; Zhou, Zhi-Wei; Liang, Jun; Duan, Wei; Chowbay, Balram; Wen, Jing-Yuan; Chan, Eli; Cao, Jie; Li, Chun-Guang; Zhou, Shu-Feng

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A Pharmacokinetic Interaction Between Clarithromycin and Sirolimus in Kidney Transplant Recipient
pp. 379-381(3)
Authors: Capone, Domenico; Palmiero, Giuseppe; Gentile, Antonio; Basile, Vincenzo; Federico, Stefano; Sabbatini, Massimo; Potenza, Maria; Perfetti, Anna; Pieri, Maria; Tarantino, Giovanni

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Synergistic Cytotoxic Activity of Recombinant TRAIL Plus the Non-Genotoxic Activator of the p53 Pathway Nutlin-3 in Acute Myeloid Leukemia Cells
pp. 395-403(9)
Authors: Secchiero, Paola; Zerbinati, Carlotta; Grazia di Iasio, Maria; Melloni, Elisabetta; Tiribelli, Mario; Grill, Vittorio; Zauli, Giorgio

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