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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 8, Number 2, 2007

Articles

Ocular Disposition, Pharmacokinetics, Efficacy and Safety of Nanoparticle-Formulated Ophthalmic Drugs
pp. 91-107(17)
Authors: Bu, Hai-Zhi; Gukasyan, Hovhannes J.; Goulet, Lance; Lou, Xiao-Jing; Xiang, Cathie; Koudriakova, Tatiana

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Identification of a Novel Intestinal First Pass Metabolic Pathway: NQO1 Mediated Quinone Reduction and Subsequent Glucuronidation
pp. 137-149(13)
Authors: Hao, Haiping; Wang, Guangji; Cui, Nan; Li, Jing; Xie, Lin; Ding, Zuoqi

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Diffusion of Macromolecule Through Retina After Experimental Branch Retinal Vein Occlusion and Estimate of Intraretinal Barrier
pp. 151-156(6)
Authors: Tao, Yong; Li, Xiao-xin; Jiang, Yan-rong; Bai, Xia-bing; Wu, Bi-dong; Dong, Jian-qiang

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A Mechanistic Study on Altered Pharmacokinetics of Irinotecan by St. John's Wort
pp. 157-171(15)
Authors: Hu, Ze-Ping; Yang, Xiao-Xia; Chen, Xiao; Cao, Jie; Chan, Eli; Duan, Wei; Huang, Min; Yu, Xue-Qing; Wen, Jing-Yuan; Zhou, Shu-Feng

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Metabolism of Sanguinarine: The Facts and The Myths
pp. 173-176(4)
Authors: Dvorak, Z.; Simanek, V.

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Modulation of Neurotransmitter Release by Carbon Monoxide at the Frog Neuro-Muscular Junction
pp. 177-184(8)
Authors: Sitdikova, Guzel F.; Islamov, Rustem R.; Mukhamedyarov, Marat A.; Permyakova, Vladlena V.; Zefirov, Andrey L.; Palotas, Andras

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Transcriptional Regulation and Expression of CYP3A4 in Hepatocytes
pp. 185-194(10)
Authors: Martinez-Jimenez, Celia P.; Jover, Ramiro; Teresa Donato, M.; Castell, Jose V.; Jose Gomez-Lechon, M.

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