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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 8, Number 1, 2007

Addendum

Author Index To Volume 7
pp. i-iv(4)
Author: Publishers

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Subject Index To Volume 7
pp. v-xii(8)
Author: Publishers

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Articles

Chemoprotective and Carcinogenic Effects of tert-Butylhydroquinone and Its Metabolites
pp. 1-7(7)
Authors: Gharavi, Negar; Haggarty, Susan; S. El-Kadi, Ayman O.

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Hyperhomocysteinaemia: A Critical Review of Old and New Aspects
pp. 17-31(15)
Authors: Herrmann, Wolfgang; Herrmann, Markus; Obeid, Rima

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Scaling Factors for the Extrapolation of In Vivo Metabolic Drug Clearance From In Vitro Data: Reaching a Consensus on Values of Human Micro-somal Protein and Hepatocellularity Per Gram of Liver
pp. 33-45(13)
Authors: Barter, Zoe E.; Bayliss, Martin K.; Beaune, Philip H.; Boobis, Alan R.; Carlile, David J.; Edwards, Robert J.; Brian Houston, J.; Lake, Brian G.; Lipscomb, John C.; Pelkonen, Olavi R.; Tucke, Geoffrey T.; Rostami-Hodjegan, Amin

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The ABCA2 Transporter: Intracellular Roles in Trafficking and Metabolism of LDL-Derived Cholesterol and Sterol-Related Compounds
pp. 47-57(11)
Authors: Mack, Jody T.; Townsend, Danyelle M.; Beljanski, Vladimir; Tew, Kenneth D.

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Molecular Modeling-Guided Site-Directed Mutagenesis of Cytochrome P450 2D6
pp. 59-77(19)
Authors: de Graaf, Chris; Oostenbrink, Chris; J. Keizers, Peter H.; A. van Vugt-Lussenburg, Barbara M.; B. van Waterschoot, Robert A.; Tschirret-Guth, Richard A.; M. Commandeur, Jan N.; E. Vermeulen, Nico P.

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