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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 7, Number 8, 2006

Articles

A Personal Tribute
pp. i-ii(2)
Authors: Kamel, Amin; Prakash, Chandra

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Endogenous Glutathione Adducts
pp. 853-872(20)
Author: Blair, Ian A.

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In Vitro and In Vivo Metabolism of a Gamma-Secretase Inhibitor BMS-299897 and Generation of Active Metabolites in Milligram Quantities with a Microbial Bioreactor
pp. 883-896(14)
Authors: Zhang, Donglu; Hanson, Ronald; Roongta, Vikram; Dischino, Douglas D.; Gao, Qi; Sloan, Charles P.; Polson, Craig; Keavy, Daniel; Zheng, Ming; Mitroka, James; Yeola, Suresh

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Characterization of an Etoposide-Glutathione Conjugate Derived from Metabolic Activation by Human Cytochrome P450
pp. 897-911(15)
Authors: Zheng, Naiyu; Pang, Shaokun; Oe, Tomoyuki; Felix, Carolyn A.; Wehrli, Suzanne; Blair, Ian A.

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A Review of Nanoelectrospray Ionization Applications for Drug Metabolism and Pharmacokinetics
pp. 913-928(16)
Authors: Wickremsinhe, Enaksha R.; Singh, Gurkeerat; Ackermann, Bradley L.; Gillespie, Todd A.; Chaudhary, Ajai K.

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LC/ESI/MS Analysis of Saturated and Unsaturated Fatty Acids in Rat Intestinal Epithelial Cells
pp. 929-937(9)
Authors: Hwa Lee, Seon; Pettinella, Caterina; Blair, Ian A.

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Xenobiotic-Metabolizing Enzymes in Human Lung
pp. 939-948(10)
Authors: Zhang, Ji Y.; Fen Wang, Yue; Prakash, Chandra

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