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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 7, Number 4, 2006

Articles

Cytochrome P450 Expression in the Liver of Food-Producing Animals
pp. 335-348(14)
Author: Ioannides, Costas

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Investigation of Exenatide Elimination and Its In Vivo and In Vitro Degradation
pp. 367-374(8)
Authors: Copley, Kathrin; McCowen, Kevin; Hiles, Richard; Nielsen, Loretta L.; Young, Andrew; Parkes, David G.

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Evaluation of 170 Xenobiotics as Transactivators of Human Pregnane X Receptor (hPXR) and Correlation to Known CYP3A4 Drug Interactions
pp. 375-388(14)
Authors: Sinz, Michael; Kim, Sean; Zhu, Zhengrong; Chen, Taosheng; Anthony, Monique; Dickinson, Kenneth; Rodrigues, A. D.

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Functional Expression of Human Cytochrome P450 Enzymes in Escherichia coli
pp. 411-429(19)
Authors: Yun, Chul-Ho; Yim, Sung-Kun; Kim, Dong-Hyun; Ahn, Taeho

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Pharmacokinetic Mechanisms for Reduced Toxicity of Irinotecan by Coadministered Thalidomide
pp. 431-454(24)
Authors: Yang, Xiao-Xia; Hu, Ze-Ping; Chan, Sui Y.; Duan, Wei; Ho, Paul C.-L.; Boelsterli, Urs A.; Ng, Ka-Yun; Chan, Eli; Bian, Jin-Song; Chen, Yu-Zong; Huang, Min; Zhou

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