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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 7, Number 3, 2006

Articles

Evaluation of Microsomal Incubation Conditions on CYP3A4-Mediated Metabolism of Cyclosporine A by a Statistical Experimental Design
pp. 265-271(7)
Authors: Hermann, Monica; Kase, Eili T.; Molden, Espen; Christensen, Hege

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Prediction of Maximum Exposure in Poor Metabolizers Following Inhibition of Nonpolymorphic Pathways
pp. 295-299(5)
Authors: Collins, C.; Levy, R.; Ragueneau-Majlessi, I.; Hachad, H.

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Involvement of Cytoskeleton in AhR-Dependent CYP1A1 Expression
pp. 301-313(13)
Authors: Dvorak, Zdenek; Vrzal, Radim; Ulrichova, Jitka; Pascussi, Jean-Marc; Maurel, Patrick; Modriansky, Martin

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A Critical Evaluation of the Experimental Design of Studies of Mechanism Based Enzyme Inhibition, with Implications for In Vitro-In Vivo Extrapolation
pp. 315-334(20)
Authors: Ghanbari, F.; Rowland-Yeo, K.; Bloomer, J. C.; Clarke, S. E.; Lennard, M. S.; Tucker, G. T.; Rostami-Hodjegan, A.

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