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Current Drug Metabolism aims to cover all the latest and outstanding developments in drug metabolism and disposition. The journal serves as an international forum for the publication of timely reviews in drug metabolism. Current Drug Metabolism is an essential journal for academic, clinical, government and pharmaceutical scientists who wish to be kept informed and up-to-date with the latest and most important developments. The journal covers the following areas:

In vitro systems including CYP-450; enzyme induction and inhibition; drug-drug interactions and enzyme kinetics; pharmacokinetics, toxicokinetics, species scaling and extrapolations; P-glycoprotein and transport carriers; target organ toxicity and interindividual variability; drug metabolism and disposition studies; extrahepatic metabolism; phase I and phase II metabolism; recent developments for the identification of drug metabolites and adducts.

Publisher: Bentham Science Publishers

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Volume 5, Number 4, 2004

Book review

Review article

HIV-1 Reverse Transcriptase Inhibitors: Current Issues and Future Perspectives
pp. 283-290(8)
Authors: Locatelli, G. A.; Cancio, R.; Spadari, S.; Maga, G.

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Novel Inhibitors of HIV-1 Integration
pp. 291-304(14)
Authors: Witvrouw, M.; Maele, B. V.; Vercammen, J.; Hantson, A.; Engelborghs, Y.; Clercq, E. De; Pannecouque, C.; Debyser, Z.

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Structural Determinants and Molecular Mechanisms for the Resistance of HIV-1 RT to Nucleoside Analogues
pp. 305-316(12)
Authors: Deval, J.; Courcambeck, J.; Selmi, B.; Boretto, J.; Canard, B.

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Assays for Determination of HIV Resistance to Antiviral Drugs
pp. 317-319(3)
Authors: Baldanti, Fausto; Paolucci, Stefania; Dossena, Luca; Gerna, Giuseppe

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Resistance to HIV Protease Inhibitors: Mechanisms and Clinical Consequences
pp. 321-328(8)
Authors: Mendoza, Carmen d.; Soriano, Vincent

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Glycosidase Inhibitors as Potential HIV Entry Inhibitors?
pp. 329-361(33)
Authors: Robina, Inmaculada; Moreno-Vargas, Antonio J.; Carmona, Ana T.; Vogel, Pierre

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