Evidence-Based Pharmacological Treatment of Substance Use Disorders and Pathological Gambling
This review summarizes our current knowledge of the pharmacological treatment of substance use disorders and pathological gambling using data mainly from randomized controlled trials and meta-analyses regarding these randomized controlled trials. The review is restricted to the selection
of first and second line pharmacological treatments for smoking, alcohol dependence, opioid dependence, cocaine dependence, cannabis dependence and pathological gambling. It is concluded that great progress has been made in the last three decades and that currently evidence-based pharmacological
treatments are available for smoking cessation, alcohol and opioid dependence and pathological gambling. At the same time a series of existing and new pharmacological compounds are being tested in cocaine and cannabis dependence. The review concludes with a summary of additional strategies
to increase the effect size of already available pharmacological interventions, including polypharmacy, combining pharmacotherapy with psychotherapy and psychosocial support, and improved patient-treatment matching.
Keywords: Addiction; dependence; pathological gambling; pharmacogenomics; pharmacological treatment; receptor; review; smoking; substance use disorders; varenicline
Document Type: Research Article
Publication date: 01 March 2012
Current Drug Abuse Reviews aims to publish the highest quality reviews, meta-analyses and drug clinical trial studies on all latest advances on alcohol and drug abuse and addiction.
Book reviews are also published. The Journal will further comprise an agenda listing relevant meetings and conferences that will take place in near future, and advertisement.
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