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Home / Combinatorial Chemistry & High Throughput Screening, Volume 12, Number 1
Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

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Volume 12, Number 1, 2009

Articles

Editorial [Hot Topic: Ion Channels: Applications in Ion Channel Drug Discovery(Guest Editor: Douglas S. Krafte)]
pp. 1-1(1)
Author: Krafte, Douglas S.

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Evolution of the Human Ion Channel Set
pp. 2-23(22)
Authors: Jegla, Timothy J.; Zmasek, Christian M.; Batalov, Serge; Nayak, Surendra K.

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Port-a-Patch and Patchliner: High Fidelity Electrophysiology for Secondary Screening and Safety Pharmacology
pp. 24-37(14)
Authors: Farre, Cecilia; Haythornthwaite, Alison; Haarmann, Claudia; Stoelzle, Sonja; Kreir, Mohamed; George, Michael; Bruggemann, Andrea; Fertig, Niels

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High Throughput Electrophysiology with Xenopus Oocytes
pp. 38-50(13)
Authors: Papke, Roger L.; Smith-Maxwell, Cathy

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Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
pp. 51-63(13)
Authors: Korsgaard, Mads P.G.; Strobaek, Dorte; Christophersen, Palle

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HCN Channels as Targets for Drug Discovery
pp. 64-72(9)
Authors: Maher, Michael P.; Wu, Nyan-Tsz; Guo, Hong-Qing; Dubin, Adrienne E.; Chaplan, Sandra R.; Wickenden, Alan D.

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The Chiptip: A Novel Tool for Automated Patch Clamp
pp. 73-77(5)
Authors: Lepple-Wienhues, Albrecht; Lassen, Dirck; Hummer, Alexander; Czubayko, Uwe; Knirsch, Martina; Golubovic, Andjelko

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Free Content QPatch: The Missing Link Between HTS and Ion Channel Drug Discovery
pp. 78-95(18)
Authors: Mathes, Chris; Friis, Soren; Finley, Michael; Liu, Yi

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Free Content Use of Planar Array Electrophysiology for the Development of Robust Ion Channel Cell Lines
pp. 96-106(11)
Authors: Clare, Jeffrey J.; Chen, Mao X.; Downie, David L.; Trezise, Derek J.; Powell, Andrew J.

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Sodium Channel Inhibitor Drug Discovery Using Automated High Throughput Electrophysiology Platforms
pp. 107-122(16)
Authors: Castle, Neil; Printzenhoff, David; Zellmer, Shannon; Antonio, Brett; Wickenden, Alan; Silvia, Christopher

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Meet The Guest Editor
pp. 123-123(1)
Author: Krafte, Douglas S.

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