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Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

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Volume 11, Number 6, 2008

Articles

Development of Selective High Affinity Antagonists, Agonists, and Radioligands for the P2Y1 Receptor
pp. 410-419(10)
Authors: Houston, Dayle; Costanzi, Stefano; Jacobson, Kenneth A.; Harden, T. K.

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Massively Parallel Screening of the Receptorome
pp. 420-426(7)
Authors: Jensen, Niels H.; Roth, Bryan L.

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Over-Expression, Solubilization, and Purification of G Protein-Coupled Receptors for Structural Biology
pp. 439-462(24)
Authors: Chiu, Mark L.; Tsang, Cindy; Grihalde, Nelson; MacWilliams, Maria P.

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Antibodies Against G-Protein Coupled Receptors: Novel Uses in Screening and Drug Development
pp. 463-467(5)
Authors: Gupta, Achla; Heimann, Andrea S.; Gomes, Ivone; Devi, Lakshmi A.

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Meet The Guest Editors
pp. 468-468(1)
Authors: Siderovski, David P.; Willard, Francis S.

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Applications of High Throughput Microsomal Stability Assay in Drug Discovery
pp. 469-476(8)
Authors: Di, Li; Kerns, Edward H.; Ma, Xuewen J.; Huang, Youping; Carter, Guy T.

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Similarity Analysis of Protein Sequences Based on the Normalized Relative-Entropy
pp. 477-481(5)
Authors: Li, Chun; Wang, Jun; Zhang, Yi; Wang, Jun

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How Large Does a Compound Screening Collection Need To Be?
pp. 482-493(12)
Authors: Lipkin, Michael J.; Stevens, Adrian P.; Livingstone, David J.; Harris, C. J.

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