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Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

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Volume 9, Number 7, 2006

Articles

Serum-Stable RNA Aptamers to an Invariant Surface Domain of Live African Trypanosomes
pp. 491-499(9)
Authors: Homann, Matthias; Lorger, Mihaela; Engstler, Markus; Zacharias, Martin; Ulrich Goringer, H.

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Design and Characterization of a Functional Library for NMR Screening Against Novel Protein Targets
pp. 515-534(20)
Authors: Mercier, Kelly A.; Germer, Katherine; Powers, Robert

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Synthesis of Metallothionein-Mimic Decapeptides with Heavy Atom Signaling Properties
pp. 535-544(10)
Authors: Rivero, Ignacio A.; Gonzalez, Tania; Diaz-Garcia, Marta E.

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Exploring Structure-Activity Relationships of Tricyclic Farnesyltransferase Inhibitors Using ECLiPS® Libraries
pp. 545-558(14)
Authors: Rokosz, Laura L.; Huang, Chia-Yu; Reader, John C.; Stauffer, Tara M.; Southwick, Eileen C.; Li, Ge; Chelsky, Daniel; Baldwin, John J.

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A Gradient Descent Algorithm for Minimizing Amino Acid Coupling Reactions when Synthesizing Cyclic-Peptide Libraries
pp. 559-563(5)
Authors: Darwen, Paul J.; Tran, Tran T.; Bourne, Gregory T.; Nielson, Jonathon L.; Smythe, Mark L.

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A Directly Labeled TR-FRET Assay for Monitoring Phosphoinositide-3-Kinase Activity
pp. 565-570(6)
Authors: Yang, Xiaoke; Li, Puyao; Feldberg, Larry; Kim, Steven C.; Bowman, Michael; Hollander, Irwin; Mallon, Robert; Wolf, Stanley F.

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