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Home / Combinatorial Chemistry & High Throughput Screening, Volume 8, Number 4
Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.

Publisher: Bentham Science Publishers

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Volume 8, Number 4, 2005

Book review

Editorial [Hot Topic: Screening for Modulators of G Protein-Coupled Receptors (Guest Editor: Guido J.R. Zaman)]
pp. 283-283(1)
Author: Zaman, Guido J.R.

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Review article

G-Protein Coupled Receptor Assays: To Measure Affinity or Efficacy that is the Question
pp. 285-292(8)
Authors: Williams, C.; Sewing, A.

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The CellCard(™) System: A Novel Approach to Assessing Compound Selectivity for Lead Prioritization of G Protein-Coupled Receptors
pp. 293-299(7)
Authors: Beske, Oren; Goldbard, Simon; Turpin, Pierre

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High Content Screening for G Protein-Coupled Receptors Using Cell-Based Protein Translocation Assays
pp. 301-309(9)
Authors: Granas, Charlotta; Lundholt, Betina K.; Heydorn, Arne; Linde, Viggo; Pedersen, Hans-Christian; Krog-Jensen, Christian; Rosenkilde, Mette M.; Pagliaro, Len

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Functional G Protein-Coupled Receptor Assays for Primary and Secondary Screening
pp. 311-318(8)
Author: Eglen, Richard M.

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Using IMAP Technology to Identify Kinase Inhibitors: Comparison with a Substrate Depletion Approach and Analysis of the Nature of False Positives
pp. 319-325(7)
Authors: Singh, P.; Lillywhite, B.; Bannaghan, C.; Broad, P.

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Substrate Specificity and Novel Selective Inhibitors of TNF-α Converting Enzyme (TACE) from Two-Dimensional Substrate Mapping
pp. 327-339(13)
Authors: Lambert, Millard H.; Blackburn, R. K.; Seaton, Theresa D.; Kassel, Daniel B.; Kinder, Daniel S.; Leesnitzer, M. Anthony; Bickett, D. Mark; Warner, Janet R.; Andersen, Marc W.; Badiang, Jennifer G.; Cowan, David J.; Gaul, Michael D; Petrov, Kimberly G.; Rabinowitz, Michael H.; Wiethe, Robert W.; Becherer, J. David; McDougald, Darryl L.; Musso, David L.; Andrews, Robert C.; Moss, Marcia L.

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Rat PXR Reporter-Gene Activity Correlates with the Induction of CYP3A in Rat Precision-Cut Liver Slices
pp. 341-346(6)
Authors: Cui, Xiaoming; Thomas, Ann; Montgomery, Diana; Gu, Chunyan; Morrison, Richard A.; White, Ronald E.; Cheng, K. -C.

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Identification of Nitric Oxide Donors by Biomimetic HTS Application
pp. 347-352(6)
Authors: Balogh, Gyorgy T.; Dalmadi, Balazs; Bielik, Attila; Keseru, Gyorgy M.

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High Throughput Coagulation Analyzers Review
pp. 353-360(8)
Author: Qari, M. H.

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Recent Advances in Analytical Construct Resins
pp. 361-371(11)
Authors: Whitehead, D. M.; McKeown, S. C.; Routledge, A

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Meet the Guest Editor
pp. 373-373(1)
Author: Zaman, Guido J.R.

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