@article {Yu:2019:2158-5849:467,
title = "On-demand drug release and re-absorption from pirarubicin loaded Fe3O4@ZnO coreshell nanoparticles for targeting infusion chemotherapy for urethral carcinoma",
journal = "Materials Express",
parent_itemid = "infobike://asp/me",
publishercode ="asp",
year = "2019",
volume = "9",
number = "5",
publication date ="2019-08-01T00:00:00",
pages = "467-474",
itemtype = "ARTICLE",
issn = "2158-5849",
url = "https://www.ingentaconnect.com/content/asp/me/2019/00000009/00000005/art00011",
doi = "doi:10.1166/mex.2019.1525",
keyword = "INFUSION CHEMOTHERAPY, URETHRAL CARCINOMA, CONTROLLED RELEASE AND RE-ABSORPTION, SIDE EFFECT, ZINC OXIDE",
author = "Yu, Zhihai and Guo, Yaochun and Dai, Hong and Zeng, Baofu and Zheng, Xi and Yi, Caixia and Jiang, Nian and Liu, Yun and Huang, Xiao",
abstract = "Although standard treatment recommendations for urethral carcinoma are lacking due to its rare incidence, urethral infusion chemotherapy can be a good choice for urethral carcinoma therapy which minimizes damage to patients compared to radical cystourethrectomy and radiation therapy.
In this work, pirarubicin loaded Fe3O4@ZnO coreshell nanoparticles have been successfully synthesized. They can magnetically position in a tubular structure at will and realized on-demand pirarubicin release and re-absorption under UV radiation and darkness. As
a result, they can strongly inhibit the human urethral squamous carcinoma cells during infusion chemotherapy and give nearly no damage to normal cells after infusion chemotherapy. Overall, such nanoparticles are highly possible to be a new approach for urethral carcinoma infusion chemotherapy,
with satisfactory efficacy and slight side effects.",
}