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Single-Walled Carbon Nanotubes (SWCNTs) and Poly(3,4-ethylenedioxythiophene) Nanocomposite Microwire-Based Electronic Biosensor Fabricated by Microlithography and Layer-by-Layer Nanoassembly

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Cost-effective single-walled carbon nanotubes (SWCNTs) and poly(3,4-ethylenedioxythiophene) nanocomposite-microwire (N-MWs) electronic biosensor was fabricated by microlithography and layer-by-layer nanoassembly. Using N-MWs, we not only can achieve accurate large-scale registration and integration of nanoscale materials into a functional device, but also can enhance the sensing surface area significantly, which can open great opportunities for the cost-effectively fabrication of ultrasensitive biosensors. Using the binding assay between Protein A and Rabbit Immunoglobulin G (IgG) as a model, measurements find that the N-MWs electronic biosensor, containing carbon nanotubes (CNTs) and conductive polymers, exhibits field effect and the resistance changes upon its binding to biomolecules. The effect of the dimensions of the N-MWs on the sensitivity of the sensor has also been evaluated.
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Keywords: Electronic Biosensor; Layer-by-Layer Nanoassembly; Microlithography; Microwire; Nanocomposite

Document Type: Research Article

Affiliations: 1: Department of Electrical and Computer Engineering, Iowa State University, Iowa, 50011, USA 2: Skyworks Solutions, Inc., 01801, USA 3: John A. Paulson School of Engineering and Applied Sciences, Harvard University, Massachusetts, 02138, USA

Publication date: December 1, 2019

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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