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Biomedical Applications and Adverse Health Effects of Nanomaterials

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We summarize recent development of nanomaterials as new tools in pharmaceutical research, molecular device designing, biomedical detection and imaging. A number of nanomaterials, including carbon based nanomaterials ([email protected]82(OH)22) n , C60(OH)22 and C60(C(COOH)2)2 etc., exhibit a very high antineoplastic efficiency and show almost no toxicity in vivo and in vitro. The underlying mechanism is related with combination of the modulation of oxidative stress, reduction of the blood supply to tumor tissues and activation of the host immune system. As the potential artificial water channel, water flow rate through carbon nanotubes (CNTs) with radius of 1–2 nm was about 3 orders of magnitude faster than the conventional nonslip hydrodynamic flow. At the same time, the toxicity of nanomaterials should be noticed. However, recent studies indicate that we have some methods to reduce the toxicity of nanomaterials such as chemical modification or binding proteins on the surface.
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Document Type: Research Article

Publication date: November 1, 2012

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  • Journal for Nanoscience and Nanotechnology (JNN) is an international and multidisciplinary peer-reviewed journal with a wide-ranging coverage, consolidating research activities in all areas of nanoscience and nanotechnology into a single and unique reference source. JNN is the first cross-disciplinary journal to publish original full research articles, rapid communications of important new scientific and technological findings, timely state-of-the-art reviews with author's photo and short biography, and current research news encompassing the fundamental and applied research in all disciplines of science, engineering and medicine.
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