@article {Kim:2012:1533-4880:1903, title = "Simultaneous Determination of Serotonin and Dopamine at the PEDOP/MWCNTsPd Nanoparticle Modified Glassy Carbon Electrode", journal = "Journal of Nanoscience and Nanotechnology", parent_itemid = "infobike://asp/jnn", publishercode ="asp", year = "2012", volume = "12", number = "3", publication date ="2012-03-01T00:00:00", pages = "1903-1909", itemtype = "ARTICLE", issn = "1533-4880", eissn = "1533-4899", url = "https://www.ingentaconnect.com/content/asp/jnn/2012/00000012/00000003/art00024", doi = "doi:10.1166/jnn.2012.5169", author = "Kim, Seul Ki and Jeon, Seungwon", abstract = "Electrochemical determination of dopamine (DA) and serotonin (5-HT) have been studied at a modified glassy carbon electrode (GCE) in 0.1 M phosphate buffer solution (PBS) using cyclic voltam-metry (CV) and differential pulse voltammetry (DPV) at pH 7.4, all over the interfering biomolecule ascorbic acid (AA). The GCE was modified by palladium-functionalized, multi-walled carbon nano-tubes (MWCNTs-Pd) with electrochemical deposition of poly 3,4-ethylenedioxy pyrrole (PEDOP), denoted as PEDOP/MWCNTs-Pd/GCE, and investigated by SEM and EIS experiments. The highly electrocatalytic activity of the modified electrode toward 5-HT and DA was demonstrated from the sensitive and well-separated voltammetric experiment. The oxidation peaks found were 0.165 and 0.355 mV for DA and 5-HT, respectively. The composite film shows a significant accumulation effects on two species, as well as the mutual interference among the analytes. This biosensor was best in response compared to other modified electrodes made in the same lab. The lowest detection limits were found to be 5.0 \texttimes 109 and 1.0 \texttimes 108 for 5-HT and DA, respectively. The respective linear ranges were determined as 1.0 \texttimes 107 to 2.0 \texttimes 104 and 1.0 \texttimes 107 to 2.0 \texttimes 104 for 5-HT and DA.", }