@article {Lee:2009:1533-4880:7181, title = "A Surface Acoustic Wave-Based Immunosensing Device Using a Nanocrystalline ZnO Film on Si", journal = "Journal of Nanoscience and Nanotechnology", parent_itemid = "infobike://asp/jnn", publishercode ="asp", year = "2009", volume = "9", number = "12", publication date ="2009-12-01T00:00:00", pages = "7181-7185", itemtype = "ARTICLE", issn = "1533-4880", eissn = "1533-4899", url = "https://www.ingentaconnect.com/content/asp/jnn/2009/00000009/00000012/art00074", doi = "doi:10.1166/jnn.2009.1662", keyword = "SAW, IMMUNOSENSING, NANOCRYSTALLINE ZNO, DNP, ZNO/SI", author = "Lee, Dae-Sik and Lee, Jun Hwang and Luo, Jikui and Fu, Yongqing and Milne, William I. and Maeng, Sunglyul and Jung, Mun Yeon and Park, Sun Hee and Yoon, Hyun C.", abstract = "The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axis-oriented crystallite with grain size of 40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl)aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 2020,000 ng/ml.", }