Postmortem Changes in Skeletal Muscle Can Be Expressed by Hounsfield Unit Measurements in Postmortem Computed Tomography—A Murine Model Study
Purpose: The aim of the present study was to assess time-dependent changes in postmortem images of mouse skeletal muscle that were obtained with a small animal CT scanner. Materials and methods: Mice were euthanized and time-dependent changes in postmortem computed tomography (PMCT) images of skeletal muscle were recorded for 11 elapsed intervals: at the confirmed time of cardiac arrest, and at 0.5, 1, 2, 3, 6, 12, 24, 36, 48, and 72 hours after death. After acquiring PMCT images, skeletal muscle was removed and prepared for histological evaluation. Histological images and PMCT images of the skeletal muscle were then compared. Hounsfield unit (HU) measurements were obtained for the skeletal muscle PMCT images at each interval and time-dependent changes were examined. Results: Time-dependent changes were observed in histological images of skeletal muscle, but not in PMCT images. Time-dependent changes were detectable by HU values of skeletal muscle. Conclusion: Postmortem changes in skeletal muscle tissue appear as decreases in HU values on PMCT.
No Reference information available - sign in for access.
No Citation information available - sign in for access.
No Supplementary Data.
No Article Media
Document Type: Research Article
Publication date: February 1, 2019
More about this publication?
- Journal of Medical Imaging and Health Informatics (JMIHI) is a medium to disseminate novel experimental and theoretical research results in the field of biomedicine, biology, clinical, rehabilitation engineering, medical image processing, bio-computing, D2H2, and other health related areas.
- Editorial Board
- Information for Authors
- Subscribe to this Title
- Ingenta Connect is not responsible for the content or availability of external websites