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Nanoparticle-Based Drug Delivery Systems for Enhanced Tumor-Targeting Treatment

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The encapsulation of targeting agents into nanoscale drug delivery systems (DDS) for cancer therapy has received considerable attention in recent years. The thriving area of cancer nanotechnology provides a unique and comprehensive anticancer approach through early diagnosis, prediction, prevention, and personalized medical therapy, preferentially vital in target-specific drug curative strategies. In this review, the concept of cancer nanotechnology and its areas of specialty are introduced, followed by a detailed presentation of specific targeting methods and various nanoparticle (NP) drug delivery systems. The technical bottleneck attached to the clinical translation and nanotoxicity issues is emphasized for future breakthroughs, that will boost drug efficacy to a higher level with the assistance of nanotechnology.
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Keywords: CANCER NANOTECHNOLOGY; CLINICAL TRANSFORMATION; DRUG DELIVERY SYSTEMS; IMPROVED ANTICANCER EFFICACY; NANOTOXICITY; TARGETING STRATEGIES

Document Type: Review Article

Publication date: January 1, 2019

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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