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A Synthetic Garden of State of the Art Natural Protein Nanoarchitectures Dispersed in Nanofluids

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As a significant discovery in the 20th century, carbon nanotubes are attracting particular attention in many unique fields such as electronics, catalysts, hydrogen storage composites, gas sensors, drug delivery, medical diagnostics, therapeutics and nanofluids. In this project, we focus on selfassembled synthetic special natural protein α-lactalbumin nanotubes with different (straight, waved, coiled, regularly bent, branched, beaded) shapes, nanospherical particles, nanorods, nanowires, nanopores, polyhedral (hexagonal network, spherical, cubic) nanostructures, nanochannels, nanofibers, nanosheets, nanoleaves, nanowave branched structures, nanobeads, nanoflowers, nanocapsules, novel nano-hybrids consisting of tubes and rods (new core-shell), nanocrystal shapes, apiary or cobweb, branched nanotubes with Y-junctions, nano membrane structures, nano sweep symmetrical shape, nano sponge structures, nano helical homogeneous structures and nano perpendicular and horizontal stable hollow single-walled natural protein nanotubes (NPNTs). These were successfully synthesized by the chemical hydrolysis sol–gel method and partial biochemical enzymatic hydrolysis by cleavage sites (Asp-X and Glu-X) of the milk protein α-lactalbumin by using various organic surfactants, pH controller functions and divalent metallic salt ions as a binding site or ions ligand formation between two bio-based building blocks to form remarkable various new morphologies in appearance of nanoemulsions and clear green nanofluids, for application in the diet nutrition food science and pharmaceutical industry. The characterization by SEM, TEM, XRD and Raman spectroscopy (specific D and G bond in protein nanotubes) confirmed the novelty of these products.
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Document Type: Research Article

Publication date: June 1, 2011

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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