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SARAMAint: The Complementarity Plot for Protein–Protein Interface

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Following our previous report of a graphical structural validation tool for single domain globular proteins namely the Complementarity Plot (SARAMA, available at, here we report the further development of the software (SARAMAint) for protein–protein interfaces available in the same webpage as a separate download link ( to be effectively used not only to estimate the overall quality of a protein–protein complex but also to assess the individual quality of packing and electrostatics of residues embedded at the interface, in many cases arising due to coordinate errors, especially in low resolution structures. The plot could also be useful for the detailed residue-wise investigation of interfaces in realistic atomic models built for protein complexes in the absence of actual experimental data.
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Document Type: Short Communication

Publication date: December 1, 2014

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  • Journal of Bioinformatics and Intelligent Control (JBIC) is an international journal that publishes research articles in areas of the bioinformatics and intelligent control. JBIC is aimed to provide an international forum for the exchange of ideas and new scientific and technological findings to disseminate information and promote the transfer of knowledge between professionals in academia and industry. The journal publishes original research papers; review papers; technical reports and notes; short communications focused on emerging new developments in these research areas.
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