@article {Bubbly:2015:2168-1996:227,
title = "Synthesis, Characterization and Biological Activity Studies on 6-Alkyl-5,6-Dihydrobenzoimidazo [1,2-c]Quinazoline Derivatives",
journal = "Journal of Advanced Physics",
parent_itemid = "infobike://asp/jap",
publishercode ="asp",
year = "2015",
volume = "4",
number = "3",
publication date ="2015-09-01T00:00:00",
pages = "227-231",
itemtype = "ARTICLE",
issn = "2168-1996",
eissn = "2168-2003",
url = "https://www.ingentaconnect.com/content/asp/jap/2015/00000004/00000003/art00012",
doi = "doi:10.1166/jap.2015.1220",
keyword = "NMR, ANTIMICROBIAL ACTIVITY, BENZIMIDAZOQUINAZOLINE DERTIVATIVES, XRD",
author = "Bubbly, S. G. and Gudennavar, S. B. and Gowda, N. M. Nanje and Gayathri, V.",
abstract = "Reaction of aminophenyl benzimidazole with propionaldehyde, i-butyraldehyde and i-valeraldehyde in alcohol resulted in the ethyl, isopropyl and isobutyl derivatives (I, II and III) of dihydrobenzoimidazo[1,2-c] quinazoline, respectively. All the products were characterized
by elemental analysis, IR, UV-Vis, 1H NMR, 13C NMR and X-ray crystal structure analysis. The antimicrobial activities of these compounds against four bacterial strains (Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas) and two fungal
strains (Cryptococcus neoformans and Candida albicans) were evaluated. Compounds I and III crystallized in the orthorhombic Pna21 space group whereas the compound II crystallized in the monoclinic P21/c space group. The structures I,
II and III were solved and refined to R-values of 0.0336, 0.0353 and 0.0387 respectively. A comparative study of the crystal structures of these compounds is also given in this paper.",
}