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Porous Silicon Myoglobin Immunosensor

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Timely detection of myocardial infarction is important to save the life of a patient. Myoglobin is an important marker of myocardial infarction. With the onset of myocardial infarction, level of myoglobin starts to enhance in serum, so detection of its level is clinically important. The specificity of antibody and sensitivity of electrochemical detection are used in our work to develop a porous silicon based immunosensor for the detection of myoglobin at different concentrations. Porous silicon is well known for its very large surface area and surface dependent electronic properties which can be exploited for development of an immunosensor. Technique of cyclic voltammetry is used for immunosensing. This technique is quite capable of detecting changes in capacitance or resistance of electrode as a result of binding of antigen.
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Document Type: Research Article

Publication date: July 1, 2014

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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