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Can Quality Control of Radiopharmaceuticals be Done Using Water and Ethanol?

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The quality control of radiopharmaceuticals is recommended by all regulatory agency around the world and is prescribed in the mains pharmacopoeias. However, for developing and underdeveloped countries the cost related to the quality control is high. In this study we developed novel techniques using water and ethanol for the quality control of radiopharmaceuticals, like 99mTc-MDP and 99mTc-DTPA. The results revealed that is possible to change acetone by water or a mix of water ethanol (ethanol:water) in the both radiopharmaceuticals analyzed with the same result from the pharmacopeial technique using acetone. These results may represent a evolution and may be used for hospital nuclear pharmacies and radiopharmacies (industry or centralized) all around the world and specially by developing and underdeveloped countries.
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Document Type: Research Article

Publication date: 15 May 2012

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  • ADVANCED SCIENCE LETTERS is an international peer-reviewed journal with a very wide-ranging coverage, consolidates research activities in all areas of (1) Physical Sciences, (2) Biological Sciences, (3) Mathematical Sciences, (4) Engineering, (5) Computer and Information Sciences, and (6) Geosciences to publish original short communications, full research papers and timely brief (mini) reviews with authors photo and biography encompassing the basic and applied research and current developments in educational aspects of these scientific areas.
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