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A Distinctive Drug Delivery System Focused on Contemporary Drugs

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Usage of drugs by patients with and without prescription by medical supervisor has been increased in recent years. Most of such drugs in markets lack good physico-chemical properties and needs to be administered at higher volumes in multiple doses and this leads to major side effects in patients. In this review, we have focused on three such drugs, ramipril (antihypertensive), azithromycin (antibacterial) and fluconazole (antifungal) that has been extensively used. It is seen that among the various methods adapted so far, nano scaled drug delivery system serves best owing to their droplet size reduction in the nano range that would enhance the drug's efficacy. Also, inclusion of essential oils in this system demonstrated superior antimicrobial activity with no toxic effects, and thus, could be exclusively used in the preparation of antibiotics. Further, this essential oil based oral formulation shows best solubilization for all three drugs, methodology adopted for their preparation is simple and exhibits good thermodynamic stability. Hence, implementing the potential of this system for these drugs would bring a new outlook in modern nanopharmaceutics.
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Keywords: AZITHROMYCIN; CLOVE OIL; DRUG DELIVERY SYSTEM; ESSENTIAL OILS; FLUCONAZOLE; RAMIPRIL

Document Type: Review Article

Publication date: July 1, 2014

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  • Advanced Science, Engineering and Medicine (ASEM) is a science, engineering, technical and medical journal focused on the publishing of peer-reviewed multi-disciplinary research articles dealing with all fundamental and applied research aspects in the areas of (1) Physical Sciences, (2) Engineering, (3) Biological Sciences/Health Sciences, (4) Medicine, (5) Computer and Information Sciences, (6) Mathematical Sciences, (7) Agriculture Science and Engineering, (8) Geosciences, and (9) Energy/Fuels/Environmental/Green Science and Engineering.
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