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Free Content Breaking the Rules: Nonclassic Appearances of Parathyroid Adenomas

At many institutions, 4D-CT has become the first-line technique for localizing candidate parathyroid adenomas before surgical resection. The appearance of the classic parathyroid adenoma on 4D-CT is well described in the literature, including enhancement pattern, morphology, and typical locations. However, readers of 4D-CT are quick to learn that many parathyroid adenomas do not conform to this conventional appearance. We will review both the classic appearance of parathyroid adenoma on 4D-CT as well as variations in appearance and location that are important to know for successful lesion localization. Familiarity with histologically proved adenomas that deviate from the classic appearance enables practicing neuroradiologists to more effectively identify potential candidate lesions, aiding the surgeon in rendering a cure.

Learning Objective: To describe the nonclassic appearance of parathyroid adenomas to improve preoperative identification of candidate lesions

Keywords: PTH = parathyroid hormone

Document Type: Research Article

Publication date: July 1, 2022

More about this publication?
  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings including the annual ASNR meeting as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing quiz-based self-assessment activities through the ASNR Education Connection portal.

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