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Free Content Arterial Spin-Labeling Perfusion for Neuroradiologists: The Essentials

Arterial spin-labeling is an increasingly used advanced imaging technique that can assess perfusion without the administration of IV contrast. There is a myriad of clinical uses for arterial spin-labeling that are important to the practice of neuroradiology. In this pictorial review, we provide an image-rich guide to the different clinical applications of arterial spin-labeling with a focus on the essential imaging findings. Covered areas include the applications of arterial spin-labeling in tumors, cerebrovascular disease, arteriovenous malformation, infection, and dementia. A mastery of arterial spin-labeling provides an important tool in the neuroradiologist's arsenal to best assist the ordering clinician in arriving at the correct diagnostic interpretation.

Learning Objective: To describe the various clinical applications of arterial spin-labeling and their associated imaging findings

Keywords: ASL = arterial spin-labeling; MELAS = mitochondrial encephalomyopathy with lactic acidosis and strokelike episodes; PRES = posterior reversible encephalopathy syndrome; pCASL = pseudocontinuous ASL

Document Type: Research Article

Publication date: July 1, 2022

More about this publication?
  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings including the annual ASNR meeting as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing quiz-based self-assessment activities through the ASNR Education Connection portal.


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