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Free Content Neuroimaging Findings of SARS-CoV-2 Infection

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This review article is a pictorial review of the wide variety of brain and spine CT and MR imaging findings related to coronavirus disease 2019 (COVID-19) in patients with neurologic deficits. By classifying CNS manifestations according to their pathogenesis, we provide different examples of vascular, immunologic, infectious, and miscellaneous complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We present cases encountered during the pandemic, retrieved from a large health system.

Learning Objectives: To review the spectrum of common and uncommon brain and spine neuroimaging findings of COVID-19 and describe the key imaging features for each finding

Keywords: ACE2 = angiotensinā€converting enzyme 2; ADEM = acute disseminating encephalomyelitis; BBE = Bickerstaff brainstem encephalitis; CLOCC = cytotoxic lesion of the corpus callosum; COVID-19 = coronavirus disease 2019; FCA = focal cerebral arteriopathy; GBS = Guillain-Barre syndrome; IgG = immunoglobulin G; MFS = Miller-Fisher syndrome; PCR = polymerase chain reaction; PRES = posterior reversible encephalopathy syndrome; SARS = severe acute respiratory syndrome; SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2; SLE = systemic lupus erythematosus; anti-GQ1b IgG = antiganglioside complex 1b IgG

Document Type: Research Article

Publication date: July 1, 2022

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  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings including the annual ASNR meeting as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing quiz-based self-assessment activities through the ASNR Education Connection portal.

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