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Home / Neurographics, Volume 10, Number 4

Free Content The Transsphenoidal Encephalocele: Associations and Elusive Origins

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Authors: Kelsch, R.D.; Tarhuni, M.A.; Saon, M.; Fischbein, N.J.; Khan, A.-M.

Source: Neurographics, Volume 10, Number 4, 1 August 2020, pp. 236-240(5)

Publisher: American Society of Neuroradiology

DOI: https://doi.org/10.3174/ng.2000007

Transsphenoidal encephaloceles comprise a rare subset of congenital basal encephaloceles in which brain tissue and overlying meninges herniate through an embryologic defect in the body of the sphenoid bone. The pathogenesis is thought to be multifactorial, possibly beginning with neural crestopathic arrest or insult, which results in subsequent mechanical and in utero events. Importantly, associated anomalies, such as optic, vascular, and endocrine abnormalities, can occur in association with transsphenoidal encephaloceles. As such, a cross-sectional multimodality approach is required to fully elucidate the extent of abnormalities, including CT, CTA, MR imaging, and/or MRA for complete characterization.

Keywords: TE = transsphenoidal encephalocele

Document Type: Research Article

Publication date: August 1, 2020

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  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings, including the annual meeting of the ASNR as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing activity evaluations through the ASNR Education Connection website: https://www.pathlms.com/asnr
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