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Free Content Head and Neck Paragangliomas: CT, MR, and 68Ga-DOTATATE PET Imaging

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Paragangliomas are rare neuroendocrine tumors that result from the abnormal migration of neural crest progenitor cells, or paraganglia, during embryonic development. Paraganglia in the head and neck migrate along a branchial mesoderm; therefore, head and neck paragangliomas may occur anywhere along the branchiomeric distribution. Head and neck paragangliomas demonstrate a number of characteristic features, such as common anatomic locations, symptomatology, associated genetic mutations, and appearance on multimodal imaging. Understanding these important attributes can allow for a prompt and accurate diagnosis. This article provides a pictorial review of the common imaging features of head and neck paragangliomas.

Learning Objective: Describe the multimodal imaging appearance of head and neck paragangliomas and their common anatomic locations.
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Keywords: 111In = indium 111; DOTA = dodecanetetraacetic acid; ECA = external carotid artery; HNPGL = head and neck paraganglioma; PGL = paraganglioma; SDH = succinate dehydrogenase; SSTR = somatostatin receptor; TATE = tyrosine-3-octreotate

Document Type: Research Article

Publication date: February 1, 2020

More about this publication?
  • Neurographics is the peer-reviewed, bimonthly educational journal of the American Society of Neuroradiology. The journal comprises articles selected from material presented at the ASNR Annual Meeting. Neurographics also publishes other high-quality submissions that are primarily educational and have a high emphasis on a pictorial approach. Neurographics offers CME credit for reading review articles and completing quiz-based self-assessment activities.

    Visit to view all available CME courses.

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