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Free Content A Review of Fetal Brain Pathology Acquired In Utero

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In utero MR imaging is used increasingly often to assist with the diagnosis of fetal brain abnormalities, and this increased use is supported by proved improvements in diagnostic accuracy compared with sonography. Fetal brain pathology may be considered developmental or acquired, though these definitions are simplistic, and there may be overlap between the 2 entities. We presented an analysis of the cases from the MERIDIAN (MR imaging to enhance the diagnosis of fetal developmental brain abnormalities in utero) cohort that fit our definitions of acquired pathologies and provided a pictorial review of the typical imaging appearances as well as provided prevalence data on acquired brain pathology.

Learning Objective: To recognize the acquired pathologies that can commonly be demonstrated with fetal brain MR imaging.

Keywords: CMV = cytomegalovirus; DVSET = dural venous sinus ectasia with thrombosis; MERIDIAN = MR imaging to enhance the diagnosis of fetal developmental brain abnormalities in utero; TORCHES = toxoplasmosis, other, rubella, cytomegalovirus, herpes, syphilis; US = ultrasonography; VGAM = vein of Galen aneurysmal malformation; gw = weeks of gestation; iuMR = in utero MR

Document Type: Research Article

Publication date: February 1, 2019

More about this publication?
  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings including the annual ASNR meeting as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing quiz-based self-assessment activities through the ASNR Education Connection portal.

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