Skip to main content

Free Content Leptomeningeal Neoplasm and Mimics: A Pictorial Review

Download Article:
Leptomeningeal enhancement is seen in a variety of primary and metastatic neoplasms. Other conditions, including inflammatory disease, infection, and infarction, can also present with leptomeningeal enhancement. MR imaging has a critical role in the identification of leptomeningeal disease; however, the differential diagnosis of leptomeningeal enhancement is broad, and clues to the diagnosis involve evaluation of the pattern and distribution of enhancement, associated imaging findings, the patient's clinical presentation, and, ultimately, CSF analysis. The purpose of this pictorial review was to familiarize the radiologist with imaging manifestations of leptomeningeal disease across a broad range of neoplastic and non-neoplastic processes.

Learning Objective: To review the imaging manifestations of leptomeningeal disease in a broad range of neoplastic and non-neoplastic mimicking entities.

Keywords: CSF = cerebrospinal fluid; DWI = diffusion-weighted image; MPRAGE = magnetization-prepared rapid acquisition of gradient echo; MS = multiple sclerosis; SMART = stroke-like migraine attacks after radiation therapy; TB = tuberculous

Document Type: Research Article

Publication date: 01 July 2017

More about this publication?
  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings, including the annual meeting of the ASNR as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing activity evaluations through the ASNR Education Connection website: https://www.pathlms.com/asnr
  • Editorial Board
  • Information for Authors
  • Membership Information
  • Order a Print Copy
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content