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Free Content Clinical Vignette: Role of Susceptibility-Weighted Imaging in Predicting Stroke Evolution

Susceptibility-weighted imaging provides information about blood oxygenation levels. Deoxyhemoglobin is increased in hypoperfused tissue. Accordingly, the draining veins in an ischemic area may reveal abnormal hypointensity. We report serial MR imaging in a boy with acute ischemic stroke and show the ability of susceptibility-weighted imaging to depict areas of critical perfusion, comparable with dynamic susceptibility contrast perfusion-weighted imaging and arterial spin-labeling. Our report confirms that susceptibility-weighted imaging may provide noninvasive data about brain tissue at risk for infarct progression by focusing on venous drainage.

Keywords: ACA = anterior cerebral artery; ADC = apparent diffusion coefficient; AIS = acute ischemic stroke; ASL = arterial spin-labeling; DSC-PWI = dynamic susceptibility contrast perfusion-weighted imaging; DWI = diffusion-weighted imaging; ICA = internal carotid artery; MCA = middle cerebral artery; MRA = magnetic resonance angiography; MTT = mean transit time; SWI = susceptibility-weighted imaging; mIP = minimum intensity projection; rCBF = relative cerebral blood flow

Document Type: Research Article

Publication date: December 1, 2013

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  • Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings, including the annual meeting of the ASNR as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing activity evaluations through the ASNR Education Connection website: https://www.pathlms.com/asnr
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