Blood-Brain-Barrier Imaging in Brain Tumors: Concepts and Methods
Keywords: BBB = Blood-Brain Barrier; CBF = cerebral blood flow; CBV = cerebral blood volume; DCE = dynamic contrast-enhanced; DSC = dynamic-susceptibility contrast; FDA = US Food and Drug Administration; GBM = glioblastoma multiforme; HIF-1α = hypoxia-inducible factor; IRF = impulse residue function; Ktrans = forward transfer coefficient; MSIVP = maximum slope of enhancement in the initial vascular phase; MVCP = microvascular cellular proliferation; MVD = microvascular density; PCT = perfusion CT; PS = permeability surface-area product; PSR = percentage signal-intensity recovery; SDF-1 = stromal derived factor-1; TDLs = tumefactive demyelinating lesions; TVA = total vascular area; VEGF = vascular endothelial growth factor; VEGFR-2 = vascular endothelial growth factor receptor-2; kep or kb = reverse transfer constant; nIAUC = initial area under the normalized time-intensity curve; nSDEP = normalized slope of the delayed equilibrium phase; rCBV = relative cerebral blood volume; rPSR = relative percentage signal-intensity recovery
Document Type: Research Article
Publication date: 01 June 2012
- Neurographics is the peer-reviewed, quarterly educational journal of the American Society of Neuroradiology. The journal includes review articles as well as high-yield case reports that have been solicited from society meetings, including the annual meeting of the ASNR as well as the American Society of Spine Radiology, the American Society of Pediatric Neuroradiology, the American Society of Functional Neuroradiology, and the American Society of Head and Neck Radiology meetings. Unsolicited educational review articles and case reports are also accepted for review at the discretion of the Editor-in-Chief. Submissions focusing on a pictorial approach to educational objectives are highly encouraged. The journal is open access and available online. CME credit is offered for reading review articles and completing activity evaluations through the ASNR Education Connection website: https://www.pathlms.com/asnr
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