Blood-Brain-Barrier Imaging in Brain Tumors: Concepts and Methods
Keywords: BBB = Blood-Brain Barrier; CBF = cerebral blood flow; CBV = cerebral blood volume; DCE = dynamic contrast-enhanced; DSC = dynamic-susceptibility contrast; FDA = US Food and Drug Administration; GBM = glioblastoma multiforme; HIF-1α = hypoxia-inducible factor; IRF = impulse residue function; Ktrans = forward transfer coefficient; MSIVP = maximum slope of enhancement in the initial vascular phase; MVCP = microvascular cellular proliferation; MVD = microvascular density; PCT = perfusion CT; PS = permeability surface-area product; PSR = percentage signal-intensity recovery; SDF-1 = stromal derived factor-1; TDLs = tumefactive demyelinating lesions; TVA = total vascular area; VEGF = vascular endothelial growth factor; VEGFR-2 = vascular endothelial growth factor receptor-2; kep or kb = reverse transfer constant; nIAUC = initial area under the normalized time-intensity curve; nSDEP = normalized slope of the delayed equilibrium phase; rCBV = relative cerebral blood volume; rPSR = relative percentage signal-intensity recovery
Document Type: Research Article
Publication date: June 1, 2012
Neurographics is the peer-reviewed, bimonthly educational journal of the American Society of Neuroradiology. The journal comprises articles selected from material presented at the ASNR Annual Meeting. Neurographics also publishes other high-quality submissions that are primarily educational and have a high emphasis on a pictorial approach. Neurographics offers CME credit for reading review articles and completing quiz-based self-assessment activities.
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