Skip to main content
padlock icon - secure page this page is secure

Free Content A Sensitive Shock Index for Real-Time Patient Assessment During Simulated Hemorrhage

Download Article:
 Download
(HTML 42.6 kb)
 
or
 Download
(PDF 909.2 kb)
 
Van Sickle C, Schafer K, Mulligan J, Grudic GZ, Moulton SL, Convertino VA. A sensitive shock index for real-time patient assessment during simulated hemorrhage. Aviat Space Environ Med 2013; 84:907–12.

Background: Shock index [SI = the ratio of heart rate (HR) to systolic arterial pressure (SAP)] is a metric used to diagnose patients at risk of impending hemorrhagic shock. We hypothesized that a metric called the compensatory reserve index (CRI), derived using computer modeling with continuous feature extraction from arterial waveforms, would provide an earlier indicator of cardiovascular instability than SI during progressive central hypovolemia. Methods: There were 15 subjects (men = 8; women = 7) who underwent progressive reduction in central blood volume induced by lower body negative pressure (LBNP) until SAP < 90 mmHg. CRI was normalized on a scale of 1 (normovolemia) to 0 (circulatory volume at which instability occurs) and displayed on a colored bar. The times at which the CRI equaled 0.6 (threshold of green to amber) or 0.3 (threshold of amber to red) were compared to a clinical threshold of SI ≥ 0.9. Results: A SI ≥ 0.9 required 22.4 ± 6.2 min (95%CI = 19 to 25.8 min). CRI reached 0.6 (amber) at 12.5 ± 4.9 min (95%CI = 9.8 to 15.3 min) when SI = 0.61 ± 0.03, and became 0.3 (red) at 20.3 ± 5.1 min (95%CI = 17.5 to 23.1 min) when SI = 0.81 ± 1.4. Conclusions: CRI provided a significantly earlier indicator of impending hemodynamic decompensation than SI ≥ 0.9 during progressive LBNP. These results support the notion that the CRI represents an improved ‘shock index’ as an indicator of impending hemorrhagic shock compared to standard vital signs.

22 References.

No Supplementary Data.
No Article Media
No Metrics

Keywords: blood pressure; central hypovolemia; lower body negative pressure; medical monitoring; pulse pressure; stroke volume

Document Type: Research Article

Publication date: September 1, 2013

More about this publication?
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more