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Open Access Graphene Nanolayers as a New Method for Bacterial Biofilm Prevention: Preliminary Results

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Biofilms are microbial communities of surface-attached cells embedded in a self-produced extracellular matrix. They have been found to play a role in a wide variety of infections, including catheter-related urinary tract and bloodstream infections, and, therefore remain a significant source of morbidity and mortality among the world's population. Recently, much attention has been devoted to the prevention of biofilm formation on implant surfaces. Nanomaterials such as graphene, characterized by antibacterial activity and low toxicity to human cells, are promising candidates for biomedical applications. This study investigates the antibacterial efficiency of graphene and specially produced graphene decorated with silver nanoparticles, obtained by one of the methods of printed electronics (spray-coating system). These methods are not only economical, but also enable the printing of layers of various thicknesses on different types of materials, including flexible and nonplanar substrates. The aim of the study was to reveal the ability of graphene and graphene-nanosilver layers to prevent the formation of Staphylococcus epidermidis biofilm on the surface of a Foley catheter.

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Document Type: Editorial

Affiliations: 1: Warsaw University of Technology, Faculty of Mechatronics, 8 Andrzeja Boboli St, 02-525 Warsaw, Poland 2: Medical University of Warsaw, Department of Orthopaedics and Traumatology, 4 Lindleya St, 02-005 Warsaw, Poland 3: Medical University of Warsaw, Department of Dental Microbiology, 1a Banacha St, 02-097 Warsaw, Poland 4: Central Clinical Hospital in Warsaw, Department of Microbiology, 1a Banacha St, 02-097 Warsaw, Poland 5: Institute of Electronic Materials Technology, 144 Wolczynska St, 00-001 Warsaw, Poland

Publication date: July 1, 2017

This article was made available online on June 16, 2017 as a Fast Track article with title: "Graphene Nanolayers as a New Method for Bacterial Biofilm Prevention: Preliminary Results".

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  • The Journal of AOAC INTERNATIONAL publishes refereed papers and reviews in the fields of chemical, biological and toxicological analytical chemistry for the purpose of showcasing the most precise, accurate and sensitive methods for analysis of foods, food additives, supplements and contaminants, cosmetics, drugs, toxins, hazardous substances, pesticides, feeds, fertilizers and the environment available at that point in time. The scope of the Journal includes unpublished original research describing new analytical methods, techniques and applications; improved approaches to sampling, both in the field and the laboratory; better methods of preparing samples for analysis; collaborative studies substantiating the performance of a given method; statistical techniques for evaluating data. The Journal will also publish other articles of general interest to its audience, e.g., technical communications; cautionary notes; comments on techniques, apparatus, and reagents.
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