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Metastatic Neuroblastoma in the Oral Cavity of a Toddler

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Neuroblastoma is a malignant pediatric tumor that originates from the sympathetic nervous system. Some tumors, especially in patients older than 18 months, show aggressive and metastatic properties. This is a report of a 20-month-old boy diagnosed with metastatic neuroblastoma that initially presented as a tumor in the oral cavity. Despite multidisciplinary treatment, the patient expired due to treatment-related toxicity. This case shows the importance of understanding metastatic tumors in the head and neck region of infants and children to ensure early diagnosis and treatment.

Keywords: CHILD; METASTATIC TUMOR; NEUROBLASTOMA; ORAL CAVITY; ORAL METASTASIS

Document Type: Case Report

Affiliations: 1: Dr. Kondo, Staff Dentist, Department of Oral Oncology, Oral and Maxillofacial Surgery and Oral Cancer Center, Tokyo Dental College, Tokyo, Japan 2: Dr. Suzuki, Assistant Professor, Department of Oral Oncology, Oral and Maxillofacial Surgery and Oral Cancer Center, Tokyo Dental College, Tokyo, Japan 3: Dr. Yamazaki, Assistant Professor, Department of Pediatrics, Keio University Hospital, Tokyo, Japan 4: Dr. Kawaida, Assistant Professor, Department of Diagnostic Pathology, Keio University Hospital, Tokyo, Japan 5: Dr. Baba, Assistant Professor, Department of Radiology, Jikei University School of Medicine, Tokyo, Japan 6: Dr. Sato, Associate Professor, Department of Oral Rehabilitation and Maxillofacial Surgery, Narita Hospital, International University of Health and Welfare, Tokyo, Japan 7: Dr. Nomura, Professor, Department of Oral Oncology, Oral and Maxillofacial Surgery and Oral Cancer Center, Tokyo Dental College, Tokyo, Japan

Publication date: January 1, 2022

More about this publication?
  • Acquired after the merger between the American Society of Dentistry for Children and the American Academy of Pediatric Dentistry in 2002, the Journal of Dentistry for Children (JDC) is an internationally renowned journal whose publishing dates back to 1934. Published three times a year, JDC promotes the practice, education and research specifically related to the specialty of pediatric dentistry. It covers a wide range of topics related to the clinical care of children, from clinical techniques of daily importance to the practitioner, to studies on child behavior and growth and development. JDC also provides information on the physical, psychological and emotional conditions of children as they relate to and affect their dental health.
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