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Pharmacological Therapy for Treatment of Recurrent Central Giant Cell Lesion in a Child

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A central giant cell lesion (CGCL) is a reactive lesion that causes destruction of bone and soft tissues and has a high recurrence rate. Only 16 percent of CGCLs are observed in children. Treatment is determined by the aggressiveness and size of the lesion and it usually involves curettage or resection. Alternative treatments, such as nasal calcitonin and intralesional corticosteroid injections, are also used. The purposes of this paper are: (1) to report the case of a nine-year-old patient who presented with a CGCL; (2) to describe its pharmacological management; and (3) to review the literature about the clinical, radiographic, and histological features of CGCL.
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Keywords: CALCITONIN; CENTRAL GIANT CELL LESION; COMBINATION THERAPIES

Document Type: Case Report

Affiliations: 1: Dr. Gonçalves is a PhD candidate, Department of Dentistry, School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil 2: Dr. Luna is an associate professor, Department of Dentistry, School of Dentistry, Federal University of Paraíba, João Pessoa, Paraíba, Brazil. 3: Dr. de Melo, Department of Dentistry, School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil 4: Dr. Nonaka, Department of Dentistry, School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil 5: Dr. Alves are associate professors, Department of Dentistry, School of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil;, Email: [email protected]

Publication date: May 1, 2019

More about this publication?
  • Acquired after the merger between the American Society of Dentistry for Children and the American Academy of Pediatric Dentistry in 2002, the Journal of Dentistry for Children (JDC) is an internationally renowned journal whose publishing dates back to 1934. Published three times a year, JDC promotes the practice, education and research specifically related to the specialty of pediatric dentistry. It covers a wide range of topics related to the clinical care of children, from clinical techniques of daily importance to the practitioner, to studies on child behavior and growth and development. JDC also provides information on the physical, psychological and emotional conditions of children as they relate to and affect their dental health.
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