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Open Access Review of CO2 as a Euthanasia Agent for Laboratory Rats and Mice

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Selecting an appropriate, effective euthanasia agent is controversial. Several recent publications provide clarity on the use of CO2 in laboratory rats and mice. This review examines previous studies on CO2 euthanasia and presents the current body of knowledge on the subject. Potential areas for further investigation and recommendations are provided.

Document Type: Research Article

Affiliations: 1: Department of Pathology, Wright State University, Dayton, Veterans Affairs Medical Center, Cincinnati, Ohio 2: Laboratory Animal Resource Center, Indiana University, Indianapolis, Indiana;, Email: [email protected] 3: The Jackson Laboratory, Sacramento, California 4: Office of Animal Resources, Harvard University, Cambridge, Massachusetts, Department of Comparative Medicine, University of Washington, Seattle, Washington 5: Office of Animal Welfare, AbbVie, North Chicago, Illinois

Publication date: September 1, 2017

More about this publication?
  • The Journal of the American Association for Laboratory Animal Science (JAALAS) serves as an official communication vehicle for the American Association for Laboratory Animal Science (AALAS). The journal includes a section of refereed articles and a section of AALAS association news. The mission of the refereed section of the journal is to disseminate high-quality, peer-reviewed information on animal biology, technology, facility operations, management, and compliance as relevant to the AALAS membership. JAALAS accepts research reports (data-based) or scholarly reports (literature-based), with the caveat that all articles, including solicited manuscripts, must include appropriate references and must undergo peer review.

    Attention Members: To access the full text of the articles, be sure you are logged in to the AALAS website.

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