Skip to main content
Home / Journal of the American Association for Laboratory Animal Science, Volume 36, Number 2

Open Access Statistics and the Issue of Animal Numbers in Research

Download Article:
The application of statistical science in helping to determine the optimum number of animals to use in experiments and in justifying the proposed number of animals is under used. Without federal guidance, the standards that constitute adequate justification are extremely variable and inconsistent from one Institutional Animal Care and Use Committee to the next. A unified approach for determining appropriate numbers of animals and ways to justify the proposed number of animals in many study protocols is provided here. This represents a first important step toward an improvement in the consistency with which researchers deal with the issue of animal numbers.

Document Type: Research Article

Affiliations: Statistical Consulting Center, Wright State University, Dayton, OH 45435

Publication date: March 1, 1997

More about this publication?

  • The Journal of the American Association for Laboratory Animal Science (JAALAS) serves as an official communication vehicle for the American Association for Laboratory Animal Science (AALAS). The journal includes a section of refereed articles and a section of AALAS association news. The mission of the refereed section of the journal is to disseminate high-quality, peer-reviewed information on animal biology, technology, facility operations, management, and compliance as relevant to the AALAS membership. JAALAS accepts research reports (data-based) or scholarly reports (literature-based), with the caveat that all articles, including solicited manuscripts, must include appropriate references and must undergo peer review.

    Attention Members: To access the full text of the articles, be sure you are logged in to the AALAS website.

    Attention: please note, due to a temporary technical problem, reference linking within the content is not available at this time

  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • Membership Information
  • Information for Advertisers
  • For issues prior to 1997
  • Institutional Subscription Activation
  • Ingenta Connect is not responsible for the content or availability of external websites

Share Content

  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content