Search Results

Pharmacogenetics of Phase I and Phase II Drug Metabolism

Authors: Crettol, Severine; Petrovic, Nenad; Murray, Michael

Source: Current Pharmaceutical Design, Volume 16, Number 2, January 2010 , pp. 204-219(16)

Publisher: Bentham Science Publishers

Gemcitabine Plus Irinotecan as First-Line Weekly Therapy in Locally Advanced and/or Metastatic Pancreatic Cancer

Authors: Neri, B.; Cipriani, G.; Grifoni, R.; Molinara, E.; Pantaleo, P.; Rangan, S.; Vannini, A.; Tonelli, P.; Valeri, A.; Pantalone, D.; Taddei, A.; Bechi, P.

Source: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, Volume 17, Numbers 11-12, 2009 , pp. 559-564(6)

Publisher: Cognizant Communication Corporation

Apoptotic cell death of human leukaemia U937 cells by ubiquinone-9 purified from Pleurotus eryngii

Authors: Bae, Jeen-Soo; Park, Jin Wook; Park, So Hyun; Park, Jung Bin; Rho, Yoon-Hwa; Ryu, Young Bae; Lee, Kun-Sik; Park, Ki-Hun; Bae, Young-Seuk

Source: Natural Product Research, Volume 23, Number 12, January 2009 , pp. 1112-1119(8)

Publisher: Taylor and Francis Ltd

Phase I/IIa Study of Combination Chemotherapy with CKD-602 and Cisplatin in Patients with Recurrent Epithelial Ovarian Cancer

Authors: Kim, Hee Seung; Kang, Sok-Bom; Seo, Sang-Soo; Han, Seung-Su; Kim, Jae Weon; Park, Noh-Hyun; Kang, Soon-Beom; Lee, Hyo-Pyo; Song, Yong Sang

Source: Annals of the New York Academy of Sciences, Volume 1171, Number 1, August 2009 , pp. 627-634(8)

Publisher: Blackwell Publishing

Evaluation of poly(d,l-lactide-co-glycolide) microspheres for the lung-targeting of yuanhuacine, a novel DNA topoisomerase I inhibitor

Authors: Zhang, Shixuan; Gao, Xiujuan; Shen, Kaihua; Yang, Puwen; Ju, Xiulan

Source: Journal of Drug Targeting, Volume 17, Number 4, May 2009 , pp. 286-293(8)

Publisher: Informa Healthcare

DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin

Authors: Orta, Manuel Lus; Mateos, Santiago; Corts, Felipe

Source: Mutagenesis, Volume 24, Number 3, 6 May 2009 , pp. 237-244(8)

Publisher: Oxford University Press

Pharmacokinetics, tissue distribution, and metabolism of novel DNA topoisomerase I inhibitor yuanhuacine in rabbit

Authors: Zhang, S. X.; Yang, P. W.; Zhang, D. C.; Dong, W. Q.; Zhang, F. H.; Sun, Y. M.

Source: Xenobiotica, Volume 39, Number 3, March 2009 , pp. 273-281(9)

Publisher: Informa Healthcare

Casein kinase I δ/ɛ phosphorylates topoisomerase IIα at serine-1106 and modulates DNA cleavage activity

Authors: Grozav, Adrian G.; Chikamori, Kenichi; Kozuki, Toshiyuki; Grabowski, Dale R.; Bukowski, Ronald M.; Willard, Belinda; Kinter, Michael; Andersen, Anni H.; Ganapathi, Ram; Ganapathi, Mahrukh K.

Source: Nucleic Acids Research, Volume 37, Number 2, 28 February 2009 , pp. 382-392(11)

Publisher: Oxford University Press

Diflomotecan, a promising homocamptothecin for cancer therapy

Authors: Kroep, Judith R; Gelderblom, Hans

Source: Expert Opinion on Investigational Drugs, Volume 18, Number 1, January 2009 , pp. 69-75(7)

Publisher: Informa Healthcare

Overexpression of carboxylesterase-2 results in enhanced efficacy of topoisomerase I inhibitor, irinotecan (CPT-11), for multiple myeloma

Authors: Yano, Hiroki; Kayukawa, Satoshi; Iida, Shinsuke; Nakagawa, Chiharu; Oguri, Tetsuya; Sanda, Takaomi; Ding, Jianming; Mori, Fumiko; Ito, Asahi; Ri, Masaki; Inagaki, Atsushi; Kusumoto, Shigeru; Ishida, Takashi; Komatsu, Hirokazu; Inagaki, Hiroshi; Suzuki, Atsushi; Ueda, Ryuzo

Source: Cancer Science, Volume 99, Number 11, November 2008 , pp. 2309-2314(6)

Publisher: Blackwell Publishing

Experimental treatment of neuroblastoma using [¹³¹I]meta-iodobenzylguanidine and topotecan in combination

Authors: McCluskey, A G; Boyd, M; Pimlott, S L; Babich, J W; Gaze, M N; Mairs, R J

Source: British Journal of Radiology, Volume 81, Supplement 1, October 2008 , pp. S28-S35(1)

Publisher: British Institute of Radiology

The Expression of Bcl-XL, Bcl-XS and p27Kip1 in Topotecan-Induced Apoptosis in Hepatoblastoma HepG2 Cell Line

Authors: Zhang, Jun; Cheng, Chao; He, Chuang-Long; Zhou, Yu-Jian; Cao, Yang

Source: Cancer Investigation, Volume 26, Number 5, June 2008 , pp. 456-463(8)

Publisher: Informa Healthcare

The role of topoisomerases and RNA transcription in the action of the antitumour benzonaphthyridine derivative SN 28049

Authors: Bridewell, David; Porter, Andrew; Finlay, Graeme; Baguley, Bruce

Source: Cancer Chemotherapy and Pharmacology, Volume 62, Number 5, October 2008 , pp. 753-762(10)

Publisher: Springer

Editorial

Author: Prudhomme, Michelle

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 6, August 2008 , pp. 576-576(1)

Publisher: Bentham Science Publishers

Pyrrolocarbazoles as Checkpoint 1 Kinase Inhibitors

Authors: Henon, Helene; Conchon, Elisabeth; Hugon, Bernadette; Messaoudi, Samir; Golsteyn, Roy M.; Prudhomme, Michelle

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 6, August 2008 , pp. 577-597(21)

Publisher: Bentham Science Publishers

Effects of isocamptothecin, a novel camptothecin analogue, on proliferation, apoptosis and telomerase activity in HaCaT cells

Authors: Lin, Jingrong; Liu, Xiaoming; Bao, Yongming; Hou, Suchun; An, Lijia; Lin, Xiran

Source: Experimental Dermatology, Volume 17, Number 6, June 2008 , pp. 530-536(7)

Publisher: Blackwell Publishing

Identification and characterization of a Drosophila ortholog of WRN exonuclease that is required to maintain genome integrity

Authors: Saunders, Robert D. C.; Boubriak, Ivan; Clancy, David J.; Cox, Lynne S.

Source: Aging Cell, Volume 7, Number 3, June 2008 , pp. 418-425(8)

Publisher: Blackwell Publishing

Polynucleotide Kinase as a Potential Target for Enhancing Cytotoxicity by Ionizing Radiation and Topoisomerase I Inhibitors

Authors: Bernstein, N. K.; Karimi-Busheri, F.; Rasouli-Nia, A.; Mani, R.; Dianov, G.; Glover, J. N.M.; Weinfeld, M.

Source: Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry, Volume 8, Number 4, May 2008 , pp. 358-367(10)

Publisher: Bentham Science Publishers

Topoisomerase I inhibitors for the treatment of brain tumors

Authors: Feun, Lynn; Savaraj, Niramol

Source: Expert Review of Anticancer Therapy, Volume 8, Number 5, May 2008 , pp. 707-716(10)

Publisher: Expert Reviews

The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y-box-binding protein-1 overexpressing tumor cells

Authors: Guay, David; Garand, Chantal; Reddy, Shanti; Schmutte, Chris; Lebel, Michel

Source: Cancer Science, Volume 99, Number 4, April 2008 , pp. 762-769(8)

Publisher: Blackwell Publishing