Search Results

Ziconotide: Neuronal Calcium Channel Blocker for Treating Severe Chronic Pain

Author: G. P. Miljanich

Source: Current Medicinal Chemistry, Volume 11, Number 23, December 2004 , pp. 3029-3040(12)

Publisher: Bentham Science Publishers

Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T

Authors: Malmberg A.B.; Gilbert H.; McCabe R.T.; Basbaum A.I.

Source: Pain, Volume 101, Number 1, January 2003 , pp. 109-116(8)

Publisher: Elsevier

Actions of intrathecal -conotoxins CVID, GVIA, MVIIA, and morphine in acute and neuropathic pain in the rat

Authors: Scott D.A.; Wright C.E.; Angus J.A.

Source: European Journal of Pharmacology, Volume 451, Number 3, 20 September 2002 , pp. 279-286(8)

Publisher: Elsevier

Composition and therapeutic utility of conotoxins from genus Conus. Patent status 1996 - 2000

Authors: Jones R.M.; Cartier G.E.; McIntosh J.M.; Bulaj G.; Farrar V.E.; Olivera B.M.

Source: Expert Opinion on Therapeutic Patents, Volume 11, Number 4, April 2001 , pp. 603-623(21)

Publisher: Informa Healthcare

An evaluation of intrathecal ziconotide for the treatment of chronic pain

Author: Jain K.K.

Source: Expert Opinion on Investigational Drugs, Volume 9, Number 10, October 2000 , pp. 2403-2410(8)

Publisher: Informa Healthcare

Bioavailability of Ziconotide in brain: influx from blood, stability, and diffusion

Authors: Newcomb R.; Abbruscato T.J.; Singh T.; Nadasdi L.; Davis T.P.; Miljanich G.

Source: Peptides, Volume 21, Number 4, April 2000 , pp. 491-501(11)

Publisher: Elsevier

Effects of intrathecal administration of ziconotide, a selective neuronal N-type calcium channel blocker, on mechanical allodynia and heat hyperalgesia in a rat model of postoperative pain

Authors: Wang Y.-X.; Pettus M.; Gao D.; Phillips C.; Scott Bowersox S.

Source: Pain, Volume 84, Number 2, 1 February 1999 , pp. 151-158(8)

Publisher: Elsevier

Alternative Intrathecal Agents for the Treatment of Pain

Authors: Hassenbusch S.J.; Garber J.; Buchser E.; Du Pen S.; Nitescu P.

Source: Neuromodulation, Volume 2, Number 2, April 1999 , pp. 85-91(7)

Publisher: Blackwell Publishing

N-type calcium channel blockers in pain and stroke

Authors: Cox B.; Denyer J.C.

Source: Expert Opinion on Therapeutic Patents, Volume 8, Number 10, October 1998 , pp. 1237-1250(14)

Publisher: Informa Healthcare

Effect of subcutaneous administration of calcium channel blockers on nerve injury-induced hyperalgesia

Authors: White D.M.; Cousins M.J.

Source: Brain Research, Volume 801, Number 1, 10 August 1998 , pp. 50-58(9)

Publisher: Elsevier

Pharmacotherapeutic potential of omega-conotoxin MVIIA (SNX-111), an N-type neuronal calcium channel blocker found in the venom of Conus magus

Authors: Bowersox S.S.; Luther R.

Source: Toxicon, Volume 36, Number 11, November 1998 , pp. 1651-1658(8)

Publisher: Elsevier

Mitochondrial dysfunction after experimental and human brain injury and its possible reversal with a selective N-type calcium channel antagonist (SNX-111)

Authors: Verweij B.H.; Muizelaar J.P.; Vinas F.C.; Peterson P.L.; Xiong Y.; Lee C.P.

Source: Clinical Neurology and Neurosurgery, Volume 99, Supplement 1, July 1997 , pp. 102-102(1)

Publisher: Elsevier

Selective blockade of N-type voltage-sensitive calcium channels protects against brain injury after transient focal cerebral ischemia in rats

Authors: Bowersox S.S.; Singh T.; Luther R.R.

Source: Brain Research, Volume 747, Number 2, 7 February 1997 , pp. 343-347(5)

Publisher: Elsevier

SNX-111, a novel, presynaptic N-type calcium channel antagonist, is neuroprotective against focal cerebral ischemia in rabbits

Authors: Perez-Pinzon M.A.; Yenari M.A.; Sun G.H.; Kunis D.M.; Steinberg G.K.

Source: Journal of the Neurological Sciences, Volume 153, Number 1, 9 December 1997 , pp. 25-31(7)

Publisher: Elsevier

Time-course and treatment response with SNX-111, an N-type calcium channel blocker, in a rodent model of focal cerebral ischemia using diffusion-weighted MRI

Authors: Yenari M.A.; Palmer J.T.; Guo H.S.; de Crespigny A.; Moseley M.E.; Steinberg G.K.

Source: Brain Research, Volume 739, Number 1, 11 November 1996 , pp. 36-45(10)

Publisher: Elsevier

Effect of continuous intrathecal infusion of -conopeptides, N-type calcium-channel blockers, on behavior and antinociception in the formalin and hot-plate tests in rats

Authors: Malmberg A.B.; Yaksh T.L.

Source: Pain, Volume 60, Number 1, January 1995 , pp. 83-90(8)

Publisher: Elsevier

Solution structure of -conotoxin MVIIA using 2D NMR spectroscopy

Authors: Basus V.J.; Nadasdi L.; Ramachandran J.; Miljanich G.P.

Source: FEBS Letters, Volume 370, Number 3, 21 August 1995 , pp. 163-169(7)

Publisher: Elsevier