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Gene Therapy for Neurological Disorders: Challenges and Future Prospects for the Use of Growth Factors for the Treatment of Parkinson's Disease

Authors: Manfredsson, Fredric p.; Okun, Michael S.; Mandel, Ronald J.

Source: Current Gene Therapy, Volume 9, Number 5, October 2009 , pp. 375-388(14)

Publisher: Bentham Science Publishers

Optimization of continuous in vivo DOPA production and studies on ectopic DA synthesis using rAAV5 vectors in Parkinsonian rats

Authors: Björklund, Tomas; Hall, Hélène; Breysse, Nathalie; Soneson, Charlotte; Carlsson, Thomas; Mandel, Ronald J.; Carta, Manolo; Kirik, Deniz

Source: Journal of Neurochemistry, Volume 111, Number 2, October 2009 , pp. 355-367(13)

Publisher: Blackwell Publishing

Comparison of transduction efficiency of recombinant AAV serotypes 1, 2, 5, and 8 in the rat nigrostriatal system

Authors: McFarland, Nikolaus R.; Lee, Jeng-Shin; Hyman, Bradley T.; McLean, Pamela J.

Source: Journal of Neurochemistry, Volume 109, Number 3, May 2009 , pp. 838-845(8)

Publisher: Blackwell Publishing

Novel Therapeutic Strategies for Epilepsy—Releasing the Gene Genie

Source: Epilepsy Currents, Volume 9, Number 1, January/February 2009 , pp. 26-27(2)

Publisher: Blackwell Publishing

Gene therapy in epilepsy

Authors: Riban, Véronique; Fitzsimons, Helen L.; During, Matthew J.

Source: Epilepsia, Volume 50, Number 1, January 2009 , pp. 24-32(9)

Publisher: Blackwell Publishing

Estrogen plays a critical role in AAV2-mediated gene transfer in ovarian cancer

Authors: SHI, Wen-fang; BARTLETT, Jeffrey S

Source: Acta Pharmacologica Sinica, Volume 29, Number 12, December 2008 , pp. 1440-1450(11)

Publisher: Blackwell Publishing

Intraventricular pre-treatment with rAAV-VEGF induces intracranial hypertension and aggravates ischemic injury at the early stage of transient focal cerebral ischemia in rats

Authors: Li, Zhaojian; Wang, Renzhi; Li, Shifang; Wei, Junji; Zhang, Ziheng; Li, Guilin; Dou, Wanchen; Wei, Yukui; Feng, Ming

Source: Neurological Research, Volume 30, Number 8, October 2008 , pp. 868-875(8)

Publisher: Maney Publishing

Adeno-associated viral vector transduction of green fluorescent protein in kidney: effect of unilateral ureteric obstruction

Authors: Ito, Keiichi; Chen, Jie; Khodadadian, Jonathan J.; Vaughan, E. Darracott; Lipkowitz, Michael; Poppas, Dix P.; Felsen, Diane

Source: BJU International, Volume 101, Number 3, February 2008 , pp. 376-381(6)

Publisher: Blackwell Publishing

Safety of adeno-associated viral vectors

Authors: Lin, Shih-Wen; Ertl, Hildegund CJ

Source: Future Virology, Volume 3, Number 5, September 2008 , pp. 491-503(13)

Publisher: Future Medicine

Towards a rAAV-based gene therapy for ADA-SCID: from ADA deficiency to current and future treatment strategies

Authors: Silver, Jared N; Flotte, Terence R

Source: Pharmacogenomics, Volume 9, Number 7, July 2008 , pp. 947-968(22)

Publisher: Future Medicine

Recombinant adeno-associated virus-mediated human kallikrein gene therapy prevents high-salt diet-induced hypertension without effect on basal blood pressure

Authors: YAN, Jiang-tao; WANG, Tao; LI, Juan; XIAO, Xiao; WANG, Dao-wen

Source: Acta Pharmacologica Sinica, Volume 29, Number 7, July 2008 , pp. 808-814(7)

Publisher: Blackwell Publishing

Boosting Anti-idiotype Immune Response with Recombinant AAV Enhances Tumour Protection Induced by Gene Gun Vaccination

Authors: Cesco-Gaspere, M.; Zentilin, L.; Giacca, M.; Burrone, O.R.

Source: Scandinavian Journal of Immunology, Volume 68, Number 1, July 2008 , pp. 58-66(9)

Publisher: Blackwell Publishing

Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene

Authors: Xie, Li-Hua; Sin, Fion; Cheng, Samuel; Cheung, Ying-Kit; Chan, Kin-Tak; Xie, Yi; Xie, Yong

Source: Cancer Immunology, Immunotherapy, Volume 57, Number 7, July 2008 , pp. 1029-1038(10)

Publisher: Springer

Recombinant AAV Viral Vectors Serotype 1, 2, and 5 Mediate Differential Gene Transfer Efficiency in Rat Striatal Fetal Grafts

Authors: Lubansu, Alphonse; Abeloos, Laurence; Bockstael, Olivier; Lehtonen, Enni; Blum, David; Brotchi, Jacques; Levivier, Marc; Tenenbaum, Liliane

Source: Cell Transplantation, Volume 16, Number 10, 2007 , pp. 1013-1020(8)

Publisher: Cognizant Communication Corporation

Process optimization of large-scale production of recombinant adeno-associated vectors using dielectric spectroscopy

Authors: Negrete, Alejandro; Esteban, Geoffrey; Kotin, Robert

Source: Applied Microbiology and Biotechnology, Volume 76, Number 4, September 2007 , pp. 761-772(12)

Publisher: Springer

Intramuscular delivery of rAAV-mediated kallikrein gene reduces hypertension and prevents cardiovascular injuries in model rats

Authors: WANG, Tao; HOU, Ling-bo; LIU, Zhen-jun; WANG, Yan; CHEN, Chun-lian; XIAO, Xiao; WANG, Dao-wen

Source: Acta Pharmacologica Sinica, Volume 28, Number 12, December 2007 , pp. 1898-1906(9)

Publisher: Blackwell Publishing

Recombinant adeno-associated virus-mediated delivery of antisense angiotensin II receptor 1 gene attenuates hypertension development

Authors: LI, Xu-guang; YAN, Jiang-tao; XU, Xi-zheng; WANG, Jia-ning; CHENG, Li-ming; WANG, Tao; ZUO, Ping; WANG, Dao-wen

Source: Acta Pharmacologica Sinica, Volume 28, Number 11, November 2007 , pp. 1737-1745(9)

Publisher: Blackwell Publishing

Generation of robust cytotoxic T lymphocytes against prostate specific antigen by transduction of dendritic cells using protein and recombinant adeno-associated virus

Authors: Mahadevan, Mahendran; Liu, Yong; You, Changxuan; Luo, Rongcheng; You, Hong; Mehta, Jawahar; Hermonat, Paul

Source: Cancer Immunology, Immunotherapy, Volume 56, Number 10, October 2007 , pp. 1615-1624(10)

Publisher: Springer

Inhibition of corneal neovascularization with endostatin delivered by adeno-associated viral (AAV) vector in a mouse corneal injury model

Authors: Lai, Li-Ju; Xiao, Xiao; Wu, June

Source: Journal of Biomedical Science, Volume 14, Number 3, May 2007 , pp. 313-322(10)

Publisher: Springer

Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness

Authors: Li, G.; Zhang, Y.; Cheng, K.; Scarpace, P.

Source: Diabetologia, Volume 50, Number 7, July 2007 , pp. 1490-1499(10)

Publisher: Springer